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Sephadex-induced granulomatous alveolitis in rat: effects of antigen manipulation

A granulomatous alveolitis, with multinuclear cell formation combined with an eosinophilic peribronchiolitis, was achieved in rats by intratracheal administration of sephadex beads (G-200, Pharmacia, Sweden). The pattern of inflammation and the degree of postgranulomatous fibrosis were substantially dampened when the particles were dispersed by ultrasonification. The animals were analyzed with bro

Glutamate, but not aspartate, is enriched in trigeminothalamic tract terminals and associated with their synaptic vesicles in the rat nucleus submedius.

To examine the possible roles of glutamate and aspartate as neurotransmitters in the nucleus submedius (Sm) of rats, the distributions of these amino acids were examined by electron microscopic immunogold labeling. High levels of glutamate were detected in trigeminothalamic tract terminals anterogradely labeled with horseradish peroxidase conjugates. These terminals also displayed a positive corre

Adsorption of hydrophobically modified starch at oil/water interfaces during emulsification

The adsorption of starch that had been hydrophobically modified with octenyl succinate anhydride (OSA) at the oil/water interface during emulsification was studied. The starch samples were of waxy barley origin and were varied in molar mass and degree of substitution (DS). The particle size of the emulsions was measured and the adsorbed amount of starch was determined through serum depletion. The

Direct and reverse mechanical modeling of an alkyd acrylic hybrid system: A morphological study

Mechanical modeling and dynamic mechanical analysis were associated to investigate the viscoelastic properties of an alkyd acrylic hybrid system in connection with its morphology, which was characterized by transmission electron microscopy. Theoretical predictions based on the interlayer model used in direct mode were successfully combined with the experimental viscoelastic data to lead to relevan

Thermodynamics and kinetics of a Go(o)over-bar proteinlike heteropolymer model with two-state folding characteristics

We present results of Monte Carlo computer simulations of a coarse-grained hydrophobic-polar G (o) over bar -like heteropolymer model and discuss thermodynamic properties and kinetics of an exemplified heteropolymer, exhibiting two-state folding behavior. It turns out that general, characteristic folding features of realistic proteins with a single free-energy barrier can also be observed in this

Measurements of collisional broadening coefficients by infrared polarization spectroscopy

We present measurements of collisional broadening coefficients, obtained at atmospheric pressure, by polarization spectroscopy. Using tunable single mode laser radiation at similar to 2 pro, high-resolution infrared polarization spectra were recorded for CO2-Ar and CO2-He binary mixtures. The recorded polarization spectra were fitted with a Lorentzian cubed function form to obtain the broadening c

Viscoelastic properties of sodium dodecyl sulfate with aluminum salt in aqueous solution

The rheological properties of wormlike micellar solutions formed by the pseudo-ternary system sodium dodecyl sulfate (SDS)-Al(NO3)(3)-H2O have been studied at a fixed molar ratio Al(NO3)(3):SDS = 5.92:1 as a function of surfactant concentration. The linear data show that solutions behave as a Maxwell fluid and there are two well-defined domains characterized by scaling laws for surfactant concentr

Re-tracing the path to third-order knowledge: How did we get here and can we move on?

The paper argues that policy-oriented educational research, specifically large-scale quantitative research, has produced a new kind of knowledge, which is herein termed third order knowledge. This expect knowledge distinquishes itself from tacit knowledge, everyday knowledge and social science knowledge through its purposes and sources. Third order knowledge is defined as knowledge of and for expe

Concentrations of plasma methylmalonic acid in 80-year-olds show only weak relation to psychological performance

Most studies of the relation between psychological performance in the elderly and deficiencies of cobalamin and folate have used methods that determine the blood concentrations of these vitamins, which might not reflect the vitamin status in the tissues. Recently, two new markers, plasma homocysteine and methylmalonic acid, have attracted growing interest since they are considered to reflect the s

Phospholipid signals and intestinal carcinogenesis

Phospholipids are an important constituent of the cell plasma membrane and are also present in most common dietary products, being particularly abundant in milk, egg, meat and beans. Phospholipids are hydrolysed by different phospholipases to generate multiple breakdown products that affect the fate of the cells. Most phospholipids such as phosphatidylcholine, lysophosphatidylcholine, phosphatidyl

Sweep Programs and Optimal Monetary Aggregation

This paper examines the admissibility of monetary aggregate groupings for the US over 1993-2001, based upon weak separability. We investigate the impact of retail and commercial demand deposit sweep programs on the separability of monetary asset groupings. Weak separability is tested Using the Swofford-Whitney and Fleissig-Whitney tests. We use Varian's measurement error adjustment procedure to el

A study on the activation peptide released from procarboxypeptidase B (CAPAP) and anionic trypsinogen in patients with acute abdominal disorders of non-pancreatic origin

Background: The activation peptide released from procarboxypeptidase B, CAPAP, is a marker of the activation of pancreatic enzymes in acute pancreatitis while anionic trypsinogen (AT) levels in urine relate to leakage of unactivated proenzymes. Data on these markers in patients suffering from severe acute abdominal disorders of nonpancreatic origin are lacking. Purpose: To examine levels of CAPAP

Bifidobacterium lactis Bb-12 and Lactobacillus salivarius UCC500 modify carboxylic acid formation in the hindgut of rats given pectin, inulin, and lactitol

The effect of Bifidobacterium lactis (Bb-12) and Lactobacillus salivarius (UCC500) on the formation of carboxylic acids (CAs) was studied in the hindgut of rats fed pectin, inulin of low solubility, and lactitol. When the pectin diet was supplemented with Bb-12, the formation of CAs was larger throughout the colon of rats, due to increased formation of acetic acid (P < 0.01) and, in the distal par

Clouds and aerosols in Puerto Rico – a new evaluation

The influence of aerosols, both natural and anthropogenic, remains a major area of uncertainty when predicting the properties and behaviour of clouds and their influence on climate. In an attempt to better understand warm cloud formation in a tropical marine environment, a period of intensive measurements took place in December 2004 in Puerto Rico, using some of the latest developments in online i

Fetal growth restriction in preterm infants and cardiovascular function at five years of age

Objectives We have previously reported an increased cardiac workload in newborn preterm small (SGA) infants, but not in infants appropriate for gestational age (AGA). We hypothesized that these cardiovascular changes win persist at follow-tip at 5 years of age. Study design We assessed blood pressure, echocardiography, and shin perfusion with laser Doppler flowmetry in 22 SGA (S21 +/- 248 g. 28.5

When is a maternal effect adaptive?

Maternal effects have become an important field of study in evolutionary ecology and there is an ongoing debate regarding their adaptive significance. Some maternal effects can act to increase offspring fitness and are called 'adaptive maternal effects'. However, other maternal effects decrease offspring fitness and there is confusion regarding whether certain maternal effects are indeed adaptive