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Flexible Rigidity and Caring Distance. : How discretion works in compulsory care.

The aim of this article was to develop the understanding of discretion in compulsory care for youth and the influence of emotional aspects in developing a collective discretionary practice. The empirical material consists of group interviews with staff at these institutions. The theoretical concepts of emotional labour and emotional energy are used to understand discretion and face-to-face interac

Pharmaceutical industry self-regulation and non-transparency : country and company level analysis of payments to healthcare professionals in seven European countries

The European pharmaceutical industry uses the alleged efficacy of self-regulation to question the need for transparency laws similar to the US Physician Payment Sunshine Act. We conducted a comparative analysis of 20 large companies’ payment disclosures in seven European countries in 2017–2019. The data was extracted as part of eurosfordocs.eu, a novel transparency project that scrapes and integra

Perovskite solar cell performance assessment

Astounding progress in achieved power conversion efficiencies of solar cells based on metal-halide perovskite semiconductors has been achieved. Viable assessment of the long-term device performance is, therefore, now the most critical aspect to reliably predict device's long-term performance. Standard testing protocols to enable cross-laboratory comparison need to be established and adopted. Apart

Improved Electrical Performance of Perovskite Photovoltaic Mini-Modules through Controlled PbI2 Formation Using Nanosecond Laser Pulses for P3 Patterning

The upscaling of perovskite solar cells to modules requires the patterning of the layer stack in individual cells that are monolithically interconnected in series. This interconnection scheme is composed of three lines, P1–P3, which are scribed using a pulsed laser beam. The P3 scribe is intended to isolate the back contact layer of neighboring cells, but is often affected by undesired effects suc

Optical Fingerprints of Polynuclear Complexes in Lead Halide Perovskite Precursor Solutions

Solvent-solute interactions in precursor solutions of lead halide perovskites (LHPs) critically impact the quality of solution-processed materials, as they lead to the formation of a variety of poly-iodoplumbates that act as building blocks for LHPs. The formation of [PbI2+n]n- complexes is often expected in diluted solutions, while coordination occurring at high concentrations is not yet well und

Modelling spatial relationships between ecosystem services and agricultural production in an agent-based model

The collective impacts of farmers' land management decisions on above ground ecosystem services (ES) and their implications for agriculture are poorly understood. Managing habitat to provide ES is costly but at the same time it can support higher yields through, e.g., pollination or natural pest control. Due to the mobility of ES-providers (bees, natural enemies) farmers providing habitat might al

Organizational and social work environment factors, occupational balance and no or negligible stress symptoms among Swedish principals - a cross-sectional study

BACKGROUND: Few studies have assessed the mental health of principals, or studied associations with both organizational and social work environment factors and occupational balance. The purpose of the present study was therefore to investigate associations between supporting and demanding organizational and social work environment factors, occupational balance and stress symptoms in principals.MET

Appearance of cytomegalovirus-specific T-cells predicts fast resolution of viremia post hematopoietic stem cell transplantation

BACKGROUND: Cytomegalovirus (CMV) specific T-cells are known to provide long-term control of CMV reactivation, which is a frequent complication of hematopoietic stem cell transplantation. We have studied 58 pediatric patients after hematopoietic stem cell transplantation who suffered from CMV reactivation to reveal which functional T cell subset is best correlating with successful reactivation res

Signature profiles of CMV-specific T-cells in patients with CMV reactivation after hematopoietic SCT

Depletion of cellular immunity as a consequence of conditioning before allogeneic hematopoietic SCT (HSCT) frequently results in CMV reactivation, which may in turn lead to life-threatening infections and require timely antiviral treatment. We have investigated the functional signatures of CMV-specific CD4 and CD8+ T-cells in 191 samples from 118 individuals. We compared healthy donors with both p

Danon disease : A focus on processing of the novel LAMP2 mutation and comments on the beneficial use of peripheral white blood cells in the diagnosis of LAMP2 deficiency

Danon disease (DD) is a monogenic X-linked disorder characterized by cardiomyopathy, skeletal myopathy and variable degrees of intellectual disability. DD develops due to mutations in the gene encoding lysosomal-associated membrane protein 2 (LAMP2). We report on a family exhibiting the clinical phenotype comprising of hypertrophic cardiomyopathy and ventricular pre-excitation, myopia and mild myo

Prognosis of pediatric patients transplanted for Ph+ chronic myeloid leukemia in the period from 1989 to 2006 in the Czech Republic

Chronic myeloid leukemia (CML) is a myeloproliferative disorder caused by clonal proliferation of primitive hematopoietic stem cell. The median age at diagnosis is 55 to 60 years with less than 10% of patients younger 20 years. Incidence of CML in children in the Czech Republic is 0.106 cases/100 thousands per year. Here we report outcome of 38 pediatric patients (median age 12.5 years; range 1.8

Low mortality of children undergoing hematopoietic stem cell transplantation from 7 to 8/10 human leukocyte antigen allele-matched unrelated donors with the use of antithymocyte globulin

Human leukocyte antigen (HLA)-matched sibling donor hematopoietic stem cell transplantation (HSCT) is available for only approximately 30% patients needing HSCT. Use of alternative donors is associated with a high incidence and severity of graft-versus-host disease (GVHD). Here we report our experience with GVHD prophylaxis using pre-transplant rabbit antithymocyte globulin (rATG), in addition to

Polyclonal, newly derived T cells with low expression of inhibitory molecule PD-1 in tonsils define the phenotype of lymphocytes in children with Periodic Fever, Aphtous Stomatitis, Pharyngitis and Adenitis (PFAPA) syndrome

Purpose: PFAPA syndrome is a benign, recurrent inflammatory disease of childhood. Tonsillectomy is one of the therapeutic options with a yet unexplained biological mechanism. We tested whether specific lymphocyte subsets recruited from blood to human tonsils participate in PFAPA pathogenesis. Methods: Paired tonsils/peripheral blood (PB) samples were investigated (a) from children with PFAPA that

Evaluation of Model-Based Iterative Reconstruction in Abdominal Computed Tomography Imaging at Two Different Dose Levels

The purpose of this study was to qualitatively evaluate recently introduced Model-based iterative reconstruction method (IMR) and routinely used iterative reconstruction algorithm iDose4 to investigate future dose reduction possibilities for abdominal CT exams. The study contained data from 34 patients who underwent abdominal CT in SkåneUniversityHospital Lund, Sweden. A low-dose scan (CTDIvol3.4

Echocardiographic assessment of chamber size and ventricular function during the first year after heart transplantation

AIMS: Detecting changes in ventricular function after orthotopic heart transplantation (OHT) using transthoracic echocardiography (TTE) is important but interpretation of findings is complicated by lack of data on early graft adaptation. We sought to evaluate echocardiographic measures of ventricular size and function the first year following OHT including speckle tracking derived strain. We also

Onset of the degradation of CVD α-Al2O3 coating during turning of Ca-treated steels

The ability to control the shape, distribution and composition of non-metallic inclusions has had an important impact on many aspects of steel making. One such impact is on the machinability. Ca-treatments have shown to be able to reduce the abrasiveness of oxide inclusions, improve chip-breaking and lead to formation of deposits that reduce tool wear. However, machining Ca-treated steels with Al2

Performance and wear mechanisms of uncoated cemented carbide cutting tools in Ti6Al4V machining

The primary tool material when machining Ti6Al4V titanium alloy is uncoated straight cemented carbide. This study examines the performance of these materials during high-speed finish turning, and uses the advanced microscopy methods of SEM, (S)TEM, XEDS, and SAED to explore the fundamental tool wear mechanisms. The wear modes include a combination of flank wear and rake cratering. Four individual