Search results

Objective: To determine whether TNF blockers increase tumour risk in patients with RA. Material and methods: The South Swedish Arthritis Treatment Group register (SSATG) comprises over 90% of anti-TNF treated patients with RA in the area. 757 patients treated with etanercept or infliximab included between 1 February 1999 and 31 December 2002 were identified. 800 patients with conventional antirheu

An efficient scheme for the simulation of quasi-static crack growth in two-dimensional linearly elastic isotropic specimens is presented. The crack growth is simulated in a stepwise manner where an extension to the already existing crack is added in each step. In a local coordinate system each such extension is represented as a polynomial of some, user specified, degree, n. The coefficients of the

Background: Preterm birth is the primary cause of the neonatal mortality and morbidity. There will be no preterm birth without a cervical softening. Nitric oxide ( NO) is shown to be a mediator of term cervical ripening. The aim of this study was to investigate mRNA expression of the three isomers of NO synthases ( NOS) and to identify them by immunohistochemistry in the human cervix at preterm bi

Dextran-conjugated EGF (EGF-dextran) has a potential use for targeted radionuclide therapy of tumors that overexpress the epidermal growth factor receptor (EGFR). There are plans to treat both bladder carcinomas and malignant gliomas with local injections of radiolabeled EGF-dextran since these tumors often express high levels of EGFR. In this report we show that EGF and EGF-dextran differentially

Geographic isolation of small populations in refugia during late Pleistocene glaciations resulted in population differentiation that in some cases lead to speciation. We report the karyotype of Microtus bavaricus, an evolutionary young and threatened rodent endemic to the Alps. Our results show that the karyotype of M. bavaricus is almost identical to that of M. liechtensteini (2N = 46, NF = 54).

Polyelectrolytes are known to mediate significant forces between macroions, or charged colloidal particles. This review highlights the research efforts made to understand the underlying mechanisms, and to predict the impact of polyelectrolyte addition to a dispersion of macroions.

Aims The aim was to determine the course of islet cell antibodies [glutamate decarboxylase (GADA), tyrosine phosphatase-like islet antigen 2 (IA-2A) and islet cell (ICA)] after the diagnosis of the diabetic patient. Methods The Diabetes Incidence Study in Sweden (DISS) attempted to prospectively enrol all newly diagnosed diabetic patients aged 15-34 years during 1992 and 1993. C-peptide and autoan

It is unclear whether high levels of antigen-specific islet antibodies [GADA (glutamic acid decarboxylase 65 antibodies) and IA2-ab (protein tyrosine phosphatase-like protein antibodies)] predict beta-cell failure in patients with onset of diabetes in adult age. Therefore, GADA and IA2-ab levels at the diagnosis of diabetes were related to fasting plasma C-peptide levels 5 yr later in 148 patients

In the first chapter we test if Purchasing Power Parity, PPP, is empirically valid and when that is not the case we test if productivity growth differences can account for the deviations from PPP by co-integration analysis. Interestingly, the results lend support in favour of PPP in several cases and when PPP is rejected GDP per capita growth rate differences seem to explain the long-run deviation

An international collaboration was organized to undertake a dosimetry exchange to enable the future combination of clinical data from different centers conducting neutron capture therapy trials. As a first step (Part I) the dosimetry group from the Americas, represented by MIT, visited the clinical centers at Studsvik (Sweden), VTT Espoo (Finland), and the Nuclear Research Institute (NRI) at Rez (

Popular Abstract in Swedish Denna avhandling handlar om expertinflytande och demokrati och fokuserar hur politiskt beslutsfattande i frågor med stort beroende av vetenskaplig expertis bör gå till för att vara demokratiskt. Studiens övergripande syfte är att från ett demokratiskt perspektiv värdera den svenska lagstiftningsprocessen om medicinsk genteknik, som kan ses som ett fall av beslutsfattandThis dissertation is about expert influence and democracy and focuses on how political decision-making about issues highly dependent on qualified scientific expertise should come about in order to be democratic. The primary purpose of the study is to evaluate, from a democratic perspective, the Swedish legislative process concerned with medical gene technology ? an archetypal case where the decisi