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Differences in the climatic debts of birds and butterflies at a continental scale

Climate changes have profound effects on the distribution of numerous plant and animal species(1-3). However, whether and how different taxonomic groups are able to track climate changes at large spatial scales is still unclear. Here, we measure and compare the climatic debt accumulated by bird and butterfly communities at a European scale over two decades (1990-2008). We quantified the yearly cha

Branched nanotrees with immobilized acetylcholine esterase for nanobiosensor applications.

A novel lab-on-a-chip nanotree enzyme reactor is demonstrated for the detection of acetylcholine. The reactors are intended for use in the RISFET (regional ion sensitive field effect transistor) nanosensor, and are constructed from gold-tipped branched nanorod structures grown on SiN(x)-covered wafers. Two different reactors are shown: one with simple, one-dimensional nanorods and one with branche

Power mapping with dynamical adjustment for improved portfolio optimization

For financial risk management it is of vital interest to have good estimates for the correlations between the stocks. It has been found that the correlations obtained from historical data are covered by a considerable amount of noise, which leads to a substantial error in the estimation of the portfolio risk. A method to suppress this noise is power mapping. It raises the absolute value of each ma

Kinetics of cisplatin binding to short r(GG) containing miRNA mimics - influence of Na(+)versus K(+), temperature and hydrophobicity on reactivity.

Nucleic acids are well recognized targets for platinum-based anticancer drugs, with RNA and DNA being kinetically comparable. In the case of RNA, previous studies have shown that the reaction between small duplex RNAs (dsRNAs) and monoaquated cisplatin (cis-Pt(NH3)2Cl(OH2)(+), ) can be followed by the metal induced hyperchromicity occurring directly after addition of to e.g. microRNA mimics. In th

Automating efficiency-targeted approximations in modelling and simulation tools: dynamic decoupling and mixed-mode integration

Modelling and simulation nowadays permeate virtually any engineering activity, requiring tools capable of managing complex models efficiently. Nonetheless, whereas modern modelling languages and tools allow to construct such models even on lightweight platforms (e.g., a laptop), the same is not true when it comes to numerically integrate those models. For the latter purpose, modellers usually purs

Wideband and Non-Dispersive Wavelet Transmission using Leaky Lens Antenna

An ultra-wideband, non-dispersive leaky lens antenna system for impulse applications has been designed, fabricated and characterized. An in-house wavelet generator is connected to the antenna to transmit 100 ps-long square pulses with center frequencies at 45, 60 and 75 GHz. It is shown that the leaky lens antenna has negligible distortion and preserves the pulse shape generated by the millimeter-

Heterogeneity in Self-Assessed Health Status Among the Elderly in India

The authors examine the observed heterogeneity in self-assessed health (SAH) among the aged in India using data on health and living conditions of the elderly in India from the 60th Round of National Sample Survey (2004-2005). Results indicate that almost one fourth of the old in India rate their health as poor, and there exists considerable interstate variations in SAH ratings. Based on hypothese

Intratumoral COX-2 inhibition enhances GM-CSF immunotherapy against established mouse GL261 brain tumors.

Immunotherapy has shown effectiveness against experimental malignant brain tumors, but the clinical results have been less convincing most likely due to immunosuppression. Prostaglandin E2 (PGE2 ) is the key immunosuppressive product of cyclooxygenase-2 (COX-2) and increased levels of PGE2 and COX-2 have been shown in several tumor types including brain tumors. In the current study, we report enha

Soil chemistry of local vegetation gradients in sandy calcareous grasslands

Acidification and N-deposition are continuous processes that alter the composition of plant communities. We investigated vegetation transitions in sandy grasslands and tested two hypotheses: (1) a shift from vegetation dominated by Koeleria glauca to one dominated by Corynephorus canescens is due to acidification and (2) a shift from vegetation dominated by K. glauca to one dominated by Arrhenathe

The art of braking : post saccadic oscillations in the eye tracker signal decrease with increasing saccade size

Abstract in Undetermined Recent research has shown that the pupil signal from video-based eye trackers contains post saccadic oscillations (PSOs). These reflect pupil motion relative to the limbus (Nyström, Hooge, & Holmqvist, 2013). More knowledge about video-based eye tracker signals is essential to allow comparison between the findings obtained from modern systems, and those of older eye tr

Low-Temperature CO Oxidation on Ni(111) and on a Au/Ni(111) Surface Alloy

From an interplay between scanning tunneling microscopy, temperature programmed desorption, X-ray photoelectron spectroscopy, and density functional theory calculations we have studied low-temperature CO oxidation on Au/Ni(111) surface alloys and on Ni(111). We show that an oxide is formed on both the Ni(111) and the Au/Ni(111) surfaces when oxygen is dosed at 100 K, and that CO can be oxidized at

A General Chemical Method to Regulate Protein Stability in the Mammalian Central Nervous System

The ability to make specific perturbations to biological molecules in a cell or organism is a central experimental strategy in modern research biology. We have developed a general technique in which the stability of a specific protein is regulated by a cell-permeable small molecule. Mutants of the Escherichia coil dihydrofolate reductase (ecDHFR) were engineered to be degraded, and, when this dest

The use of hair as an indicator of occupational (14)C contamination.

This paper presents a study in which the specific activity of (14)C in hair has been investigated as an easily determined bio-indicator of the integrated (14)C exposure (over several months). The study includes 28 Swedish workers handling (14)C-labelled compounds, or working in a (14)C-enriched environment. Hair samples from personnel at a Swedish nuclear power plant showed very low levels of (14)

Is Co-Invention Expediting Technological Catch Up? A Study of Collaboration between Emerging Country Firms and EU Inventors

Firms from emerging countries are going global, and Europe is attracting around one-third of their direct outward investments. Growing internationalization constitutes an opportunity for technological catch up. In this paper we analyze Brazilian, Indian, and Chinese cross-border inventions with European Union (EU-27) inventors, during the period 1990-2012. Our results suggest that these inventions

Search for Diphoton Events with Large Missing Transverse Energy in 7 TeV Proton-Proton Collisions with the ATLAS Detector

A search for diphoton events with large missing transverse energy is presented. The data were collected with the ATLAS detector in proton-proton collisions at root s = 7 TeV at the CERN Large Hadron Collider and correspond to an integrated luminosity of 3: 1 pb(-1). No excess of such events is observed above the standard model background prediction. In the context of a specific model with one univ

The Normal Incidence Monochromator Beamline I3 on MAX III

On the 700 MeV MAX III ring at MAX-lab, a 6.65 m off-axis eagle type monochromator beamline has recently been commissioned. The beamline is sourced by an apple type variable polarization undulator. The energy range of the beamline is 4.6-50 eV and the resolving power achieved is more than 100,000. There are two branch lines, one for angle and spin resolved photoemission studies from solids and the