The aim of the study was to evaluate the feasibility of tailored and dose-dense epirubicin and cyclophosphamide followed by docetaxel as adjuvant breast cancer therapy. Material and methods. Patients with node-positive breast cancer received either four cycles of biweekly and tailored EC (epirubicin 38-60-75-90-105-120 mg/m(2), cyclophosphamide 450-600-900-1200 mg/m(2)) followed by four cycles of

In magnetic resonance imaging (MRI), the balanced steadystate free precession (bSSFP) pulse sequence has shown to be of great interest, due to its relatively high signal-to-noise ratio in a short scan time. However, images acquired with this pulse sequence suffer from banding artifacts due to offresonance effects. These artifacts typically appear as black bands covering parts of the image and they

Abstract in Danish Hvad er det der ‘kvæær’ egentlig? Dette spørgsmål synes altid at klistre til tekster og praksisser med queer som udgangspunkt, og dets svar bliver ofte tøvende, hængende i luften – ambivalent, utydeligt og afhængig af kontekst. For den som stiller spørgsmålet, bliver svaret næsten aldrig så konkret som hen håbede på. Og for den som forventes at svare, bliver diffuse henvisninger

This paper aims at validation of an iterative receiver for multiple-input multiple-output with orthogonal frequency division multiplexing (MIMO-OFDM) systems using real-measurement channel data from an indoor scenario. The receiver performs iterative multi-user detection (MUD) and Channel Estimation (CE) via soft information from the single- user decoders. The channel measurements were performed f

Domain polarization switching in potassium dihydrogen phosphate (KH2PO4, KDP) induced by a propagating strain wave has been observed with time-resolved x-ray diffraction. A pulsed electric field with amplitude of 6 kV/cm and duration of 1 mu s was applied along the crystallographic c axis. The field-induced strain waves emanating from the sample surfaces are the result of the converse piezoelectri

As a global society we are entering an era where land areas and land-based resources are coming to the fore once again for capital accumulation and economic growth, for the first time since the end of the 18th century when Malthus forecasted a contradiction between population growth and agricultural output. That constraint on economic growth, imposed by limited land areas, was overcome by the comb

Background: Musculoskeletal disorders (MSDs) are a major reason for impaired work productivity and sick leave. In 2009, a national rehabilitation program was introduced in Sweden to promote work ability, and patients with MSDs were offered multimodal rehabilitation. The aim of this study was to analyse the effect of this program on health related quality of life, function, sick leave and work abil

The ionization signals in the liquid argon of the ATLAS electromagnetic calorimeter are studied in detail using cosmic muons. In particular, the drift time of the ionization electrons is measured and used to assess the intrinsic uniformity of the calorimeter gaps and estimate its impact on the constant term of the energy resolution. The drift times of electrons in the cells of the second layer of

Rheumatoid arthritis (RA) is a highly disabling disease affecting all structures of the joint. Understanding the pathology behind the development of RA is essential for developing targeted therapeutic strategies as well as for developing novel markers to predict disease onset. Several molecules normally hidden within the cartilage tissue are exposed to complement components in the synovial fluid u

The extent to which in-situ global mechanical tensioning (GMT) can be used to modify the residual stress state in friction stir (FS) welds is investigated in this article. Residual stress distributions have been determined by synchrotron X-ray and neutron diffraction for four sets of FS welds in high-strength AA7449-W51 and lithium containing AA2199-T8 aerospace aluminum alloys subjected to a syst

Abstract in UndeterminedMultiple-antenna handheld terminals are an integral part of the latest mobile communication systems, due to the adoption of multiple-input multiple-output (MIMO) technology. In this contribution, MIMO performances of three multiple-antenna configurations for smart phones are investigated in an urban macrocellular environment, based on an extensive MIMO measurement campaign

Time-resolved terahertz spectroscopy and Monte Carlo simulations of charge-carrier motion are used to investigate photoinduced transient conductivity in a blend of a low-band-gap polyphenylene copolymer and fullerene derivative. The optical excitation pulse generates free holes delocalized on polymer chains. We show that these holes exhibit a very high initial mobility as their initial excess ener

Ferroelectric materials exhibit a huge potential for engineering applications - ranging from electrical actuators (inverse piezoelectric effect) to sensor technology (direct piezoelectric effect). To give an example, lead zirconate titanate (PZT) is a typical perovskite ion crystal possessing ferroelectric properties. In this contribution, we are particularly interested in the modelling of microcr

Development and validation of robust molecular biomarkers has so far been limited in melanoma research. In this paper we used a large population-based cohort to replicate two published gene signatures for melanoma classification. We assessed the signatures prognostic value and explored their biological significance by correlating them with factors known to be associated with survival (vitamin D) o

Hela 122 nya arter för Blekinge – varav åtta även nya för Sverige – har hittats sedan Blekinges flora kom ut 2006. Lars Fröberg presenterar här den digra fyndlistan.

Cardiolipin is a phospholipid found in the inner mitochondrial membrane and in bacteria, and it is associated with many physiological functions. Cardiolipin has a dimeric structure consisting of two phosphatidyl residues connected by a glycerol bridge and four acyl chains, and therefore it can carry two negative charges. The pKa values of the phosphate groups have previously been reported to diffe

Caldicellulosiruptor saccharolyticus has gained reputation as being among the best microorganisms to produce H2 due to possession of various appropriate features. The quest to develop an inexpensive cultivation medium led to determine a possible replacement of the expensive component cysteine, i.e. sulphate. C. saccharolyticus assimilated sulphate successfully in absence of a reducing agent withou

We construct small-amplitude periodic water waves with multiple critical layers. In addition to waves with arbitrarily many critical layers and a single crest in each period, multimodal waves with several crests and troughs in each period are found. The setting is that of steady two-dimensional finite-depth gravity water waves with vorticity.