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Cognitive Control in Distracted Dinosaurs

Cognitive control is a skill used to control one’s own behaviour to reach a goal. We compared this skill across archosaurs by using the distraction task on American alligators, emus, chickens, and common ravens. We investigated whether the animals would still find a food reward hidden behind one of two identical opaque barriers after picking up a food distraction. Results show that all species can

Dietary index based on the Food Standards Agency nutrient profiling system and risk of Crohn's disease and ulcerative colitis

Background: Nutri-score is now widely available in food packages in Europe. Aim: To study the overall nutritional quality of the diet in relation to risks of Crohn's disease (CD) and ulcerative colitis (UC), in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. Methods: We collected dietary data at baseline from validated food frequency questionnaires. We used a dietar

Evaluating the 11-year solar cycle and short-Term 10Be deposition events with novel excess water samples from the East Greenland Ice-core Project (EGRIP)

10Be is produced by the interaction between galactic cosmic rays (GCRs) and solar energetic particles (SEPs) with the Earth's atmospheric constituents. The flux of GCRs is modulated by the varying strength of the magnetic fields of the Earth and the Sun. Measurement of 10Be concentrations from polar ice cores is thus a valuable tool to reconstruct the variations in the geomagnetic field and solar

Accurate prediction of protein assembly structure by combining AlphaFold and symmetrical docking

AlphaFold can predict the structures of monomeric and multimeric proteins with high accuracy but has a limit on the number of chains and residues it can fold. Here we show that a combination of AlphaFold and all-atom symmetric docking simulations enables highly accurate prediction of the structure of complex symmetrical assemblies. We present a method to predict the structure of complexes with cub

Cognitively defined Alzheimer's dementia subgroups have distinct atrophy patterns

INTRODUCTION: We sought to determine structural magnetic resonance imaging (MRI) characteristics across subgroups defined based on relative cognitive domain impairments using data from the Alzheimer's Disease Neuroimaging Initiative (ADNI) and to compare cognitively defined to imaging-defined subgroups. METHODS: We used data from 584 people with Alzheimer's disease (AD) (461 amyloid positive, 123

Magmatism during late Ordovician-early Silurian accretion of the Caledonides of Arctic Scandinavia : the Halti-Guolasjavri area revisited

In the Scandinavian Caledonides, evidence of syn-collisional magmatism related to extensional basin development immediately prior to late Silurian Baltica-Laurentia collision was considered restricted to exotic terranes until late Silurian ages were obtained from the Halti Igneous Complex (HIC), hosted by a thrust sheet (Corrovarre Nappe, CN) of continental affinity. Various orogenic models for th

Circulating mitochondrial long non-coding 7S RNA in primary health care patients with depression/anxiety

BACKGROUND: The significant role of long non-coding 7S RNA in controlling mitochondrial transcription highlights its importance in mitochondrial function. Considering the suggested connection between mitochondrial dysfunction and the onset of mental disorders, this study aimed to explore the potential involvement of 7S RNA in the context of depression/anxiety.RESULTS: A total of 181 patients in pr

Fostering an innovation ecosystem for a public digital health platform

This short paper explores building innovation platforms in the public sector, particularly in public healthcare, through an ecological lens. While existing research has mainly focused on the platform owner's role in orchestrating innovation, this study investigates the strategies used by public organizations and widens the net to analyse how a digital health platform’s complementing actors contrib

Quantifying the impact of Covid-19 on the energy consumption in the low-income housing in Greater London

Covid-19 has caused great challenges to the energy sector, particularly in residential buildings with low-income households. This study investigates the impact of the confinement measures due to the Covid-19 outbreak on the energy demand of seven residential archetype buildings in Greater London. Three levels of confinement for occupant schedules are proposed and compared with the base case before

ISE/ISHNE expert consensus statement on the ECG diagnosis of left ventricular hypertrophy : The change of the paradigm

The ECG diagnosis of LVH is predominantly based on the QRS voltage criteria. The classical paradigm postulates that the increased left ventricular mass generates a stronger electrical field, increasing the leftward and posterior QRS forces, reflected in the augmented QRS amplitude. However, the low sensitivity of voltage criteria has been repeatedly documented. We discuss possible reasons for this

Afterword : Storytelling Animals: Human-Nonhuman Relationships in the Arctic

A common misperception among non-arctic residents is that northern environments are less productive and more hostile to human life than other biomes; after all, it is true that in most arctic regions, traditional agriculture is generally not possible, and species richness is relatively low. Combatting such misperceptions is important because while the past century has foisted many traumatic change

Ganglioside Micelles Affect Amyloid β Aggregation by Coassembly

Amyloid β peptide (Aβ) is the crucial protein component of extracellular plaques in Alzheimer’s disease. The plaques also contain gangliosides lipids, which are abundant in membranes of neuronal cells and in cell-derived vesicles and exosomes. When present at concentrations above its critical micelle concentration (cmc), gangliosides can occur as mixed micelles. Here, we study the coassembly of th