Clear cell sarcoma of the kidney (CCSK) is a tumor affecting children with a median age of 3 years at diagnosis. The cell of origin of CCSK is unknown and data on the molecular changes giving rise to CCSK is scarce. This has hindered the identification of positive diagnostic markers and development of molecularly targeted treatment protocols for CCSK. We have characterized a panel of CCSK to gain

A simple mass balance model has been developed to assess the planetary boundary for P supply in relation to use by human society. Phosphorus sources used by humans are from fossil reserves. The model takes into account resource use rate and reserves, consumption, phosphate to food production, environmental degradation, waste and recycling. Various policy scenarios are tested from current end of pi

Acetic acid was investigated as a catalyst in steam pretreatment of corn stover. The purpose was to study ethanol production using either baker's yeast or a genetically modified pentose-fermenting version of Saccharomyces cerevisiae, KE6-12. Biogas production was investigated as an alternative for utilization of xylose. The high levels of acetic acid was found to be toxic using KE6-12. Some pentos

Patients with generalized ANCA-associated small vessel vasculitis (AAV) have a very poor outcome if the ANCA-associated vasculitis is not diagnosed, evaluated and treated properly. The introduction of treatment with immunosuppressive therapy has improved patient survival dramatically but with considerable side effects. Besides, almost 50% of surviving patients experience a relapse of vasculitis. S

Background: Few published data link overweight and obesity with measures of quality of life (QoL) including sexual health in men. Objective: To assess the association of overweight/obesity with impairment of physical and psychological QoL and sexual functions in men. Design and setting: Cross-sectional, multicentre survey of 3369 community-dwelling men aged 40-79 (mean +/- S.D., 60 +/- 11) years r

Older adults prefer to age in place, necessitating a match between person and environment, or person-environment (P-E) fit. In occupational therapy practice, home modifications can support independence, but more knowledge is needed to optimize interventions targeting the housing situation of older adults. In response, this study aimed to explore the accessibility and usability of the home environm

Purpose: The purpose of this systematic review was to summarise the evidence from randomised controlled trials examining the effectiveness of physical therapy compared with care as usual or a wait-list condition on eating pathology and on physiological and psychological parameters in patients with anorexia and bulimia nervosa. Method: EMBASE, PsycINFO, PubMed, Cumulative Index to Nursing and Allie

Climate change is leading to a disproportionately large warming in the high northern latitudes, but the magnitude and sign of the future carbon balance of the Arctic are highly uncertain. Using 40 terrestrial biosphere models for the Alaskan Arctic from four recent model intercomparison projects - NACP (North American Carbon Program) site and regional syntheses, TRENDY (Trends in net land atmosphe

Surgical site infections (SSIs) after dermatologic surgery continue to represent undesirable complications that affect patients in several aspects. The etiology and pathogenesis of SSIs are not completely understood, and as a result, current preventative measures are debatable.

Butyric acid, one of the key products formed when β-glucans are degraded by the microbiota in the colon, has been proposed to be important for colonic health. Glutamine bound to the fibre may have similar effects once it has been liberated from the fibre in the colon. Both β-glucans and glutamine are found in high amounts in malted barley. Lactobacillus rhamnosus together with malt has been shown

Determination of the subsurface geology is very important for the rock quarry industry. This is primarily done by drilling and mapping. However, in Sweden, the bedrock is often completely covered by Quaternary sediments, making the prediction quite difficult. This study shows that electrical resistivity imaging together with induced polarization proved to be very efficient in detecting fracture fr

Power spectrum analysis of heart rate variability (HRV) may provide insight into the mental state of the animal held in restricted specific experimental conditions. Determining inter-beat-interval (IBI) variations is one way to measure changes in autonomic nervous system (ANS) activity in horses. An imbalance between the sympathetic and parasympathetic nervous system can indicate pain or stress, f

Complement convertases are enzymatic complexes that play a central role in sustaining and amplification of the complement cascade. Impairment of complement function directly or indirectly leads to pathologic conditions including higher infection rate, kidney diseases, autoimmune- or neurodegenerative diseases and ischemia-reperfusion injury. An assay for direct measurement of activity of the conve

Individual T4DNA molecules, previously compacted by using a cationic surfactant (cetyltrimethylammonium bromide, CTAB), were successfully decompacted by the addition of an appropriate concentration of either alpha-cyclodextrin or beta-cyclodextrin (alpha-CD and beta-CD, respectively) due to the formation of inclusion complexes with the surfactant. The process was shown to be a non first-order tran

This article explores how the image of the USA has developed in two major Russian daily newspapers, Izvestiya and Komsomolskaya Pravda, in a time period comprised of a total 20 weeks’ of study in the years of 1984, 1994, 2004 and 2009. For Russia this time span was dramatic: it moved from seemingly stable superpower in the 1980s, over the chaos after the dissolution of the Soviet Union in the 1990

We present an expanded Wolf formalism for direct summation of long-range dipole-dipole interactions and rule-of-thumbs how to choose optimal spherical cutoff (R-c) and damping parameter (alpha). This is done by comparing liquid radial distribution functions, dipole-dipole orientation correlations, particle energies, and dielectric constants, with Ewald sums and the Reaction field method. The resul