The least squares estimator can be cast as depending only on the precision matrix of the data, similar to the weights of a global minimum variance portfolio. We give conditions under which any plug-in precision matrix estimator produces an unbiased and consistent least squares estimator for stationary time series regressions, in both low- and high-dimensional settings. Such conditions define a cla

Objective: To describe healthcare professionals’ perception of current early rehabilitation practices and their preconditions, focusing on functional and cognitive stimulation facilitated by nurses and other healthcare professionals in Scandinavian intensive care units (ICUs). Design: Cross-sectional electronic survey administered to healthcare professionals. The survey was developed in Danish, tr

Lately, interest has increased in using Virtual Reality (VR) in residential care facilities to increase accessibility to nature experiences. It is widely acknowledged that nature benefits health, and various theories exist regarding its restorative effects. Studies of virtual natural environments often start from predetermined mediating mechanisms and health outcomes. However, virtual nature is fu

The azimuthal anisotropy of particles associated with jets (jet particles) at midrapidity is measured for the first time in p-Pb and Pb-Pb collisions at sNN = 5.02 TeV down to transverse momentum (pT) of 0.5 GeV/c and 2 GeV/c, respectively, with ALICE. The results obtained in p-Pb collisions are based on a novel three-particle correlation technique. The azimuthal anisotropy coefficient v2 in high-

The production yields of the Σ(1385)± and Ξ(1530)0 resonances are measured in pp collisions at s = 13 TeV with ALICE. The measurements are performed as a function of the charged-particle multiplicity ⟨dNch/dη⟩, which is related to the energy density produced in the collision. The results include transverse momentum (pT) distributions, pT-integrated yields, mean transverse momenta of Σ(1385)± and Ξ

The focus of this study is the direct interactions of the local turbulent fields and single drops inside the anisotropic turbulent field of a high-pressure homogenizer valve scale-up model. A volume of fluid scheme is incorporated into a direct numerical simulation approach to study the deformation and breakup of drops. The numerical framework was validated by experiments in a previous study. Ther

During human embryogenesis, distinct waves of hematopoiesis give rise to various blood cell types, originating from hemogenic endothelial (HE) cells. As HE cells reside in hypoxic conditions in the embryo, we investigated the role of hypoxia in human endothelial to hematopoietic transition and subsequent hematopoiesis. Using single-cell RNA sequencing, we describe hypoxia-related transcriptional c

AU The:information Pleaseconfirmthatallheadinglevelsarerepresentedcorrectly contained in population genomic data can tell : us much about the past ecology and evolution of species. We leveraged detailed phenotypic and genomic data of nearly all living kākāpō to understand the evolution of its feather color polymorphism. The kākāpō is an endangered and culturally significant parrot endemic to Aotea

Background: In 2020, the coronavirus disease 2019 (COVID-19) pandemic caused disruptions in kidney replacement therapy (KRT) services worldwide. The aim of this study was to assess the effect of the COVID-19 pandemic in 2020 on the incidence of KRT, kidney transplantation activity, mortality and prevalence of KRT across Europe. Methods: Patients receiving KRT were included from 17 countries provid

Purpose: To examine health-related quality of life (HRQoL) and supportive care needs among young adult (YA) cancer survivors up to 3 years post-diagnosis. Methods: A national cohort of individuals diagnosed at 18–39 years with breast, cervical, ovarian, or testicular cancer, lymphoma or brain tumor was approached with surveys at 1.5 (n = 1010, response rate 67%) and 3 (n = 722) years post-diagnosi

Context. The nuclear stellar disc (NSD) is a flat and dense stellar structure at the centre of the Milky Way. Previous work has identified the presence of metal-rich and metal-poor stars in the NSD, suggesting that they have different origins. The recent publication of photometric, metallicity, proper motion, and orbital catalogues allows the NSD stellar population to be characterised with unprece

Context. Among the thousands of exoplanets discovered to date, approximately a few hundred gas giants on short-period orbits are classified as 'lonely'and only a few are in a multi-planet system with a smaller companion on a close orbit. The processes that formed multi-planet systems hosting gas giants on close orbits are poorly understood, and only a few examples of this kind of system have been

Glioblastoma presents a formidable clinical challenge because of its complex microenvironment. Here, we characterized tumor-associated foam cells (TAFs), a type of lipid droplet-loaded macrophage, in human glioblastoma. Through extensive analyses of patient tumors, together with in vitro and in vivo investigations, we found that TAFs exhibit distinct protumorigenic characteristics related to hypox

A measurement of time-dependent CP violation in D0→π+π-π0 decays using a pp collision data sample collected by the LHCb experiment in 2012 and from 2015 to 2018, corresponding to an integrated luminosity of 7.7 fb-1, is presented. The initial flavor of each D0 candidate is determined from the charge of the pion produced in the D∗(2010)+→D0π+ decay. The decay D0→K-π+π0 is used as a control channel

Delivery care in Sweden is very safe, the incidence of maternal death is 5/100 000 and perinatal death