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Background: The purpose of this study is to investigate the impact of oxygen therapy on cardiovascular outcomes in relation to sex in patients with confirmed myocardial infarction (MI). Methods: The DETermination of the role of Oxygen in suspected Acute Myocardial Infarction trial randomized 6,629 patients to oxygen at 6 L/min for 6-12 hours or ambient air. In the present subgroup analysis includi

A comprehensive understanding of the effect of green roofs on the indoor thermal comfort, under different microclimates, will help to identify key design aspects. In this study, which is the first of its kind in Brazil, the indoor thermal comfort for two different types of roofs, under different microclimates in Porto Alegre in Southern Brazil, have been compared. Coupled simulations using ENVI-me

This research aimed to evaluate a microbial fuel cell (MFC) device equipped with a novel composite polymer-electrolyte membrane consisting of the metal-organic framework and sulfonated polysulfone (SPSU/MIL-100(Fe)) for simultaneous treatment of meat poultry wastewater and power generation. The composite SPSU/MIL-100(Fe) membranes were fabricated by solution casting of polymer and characterized to

It has become necessary to estimate the quantities of runoff by knowing the amount of rainfall to calculate the required quantities of water storage in reservoirs and to determine the likelihood of flooding. The present study deals with the development of a hydrological model named Hydrologic Engineering Center (HEC-HMS), which uses Digital Elevation Models (DEM). This hydrological model was used

In this work, laser-based diagnostic techniques were developed and applied to investigate soot formation in small-scale laboratory burners as well as in practical combustion devices. Quantitative 2D laser-induced incandescence (LII) measurements often use a cylindrical lens to shape the beam and illuminate the planar region of interest. The varying laser fluence and sheet width in the imaged flame

Plant phenology plays a fundamental role in land atmosphere interactions, and its variability and variations are an indicator of climate and environmental changes. For this reason, current land surface models include phenology parameterizations and related biophysical and biogeochemical processes. In this work, the climatology of the beginning and end of the growing season, simulated by the land c

For decades, measured ice crystal number concentrations have been found to be orders of magnitude higher than measured ice-nucleating particle number concentrations in moderately cold clouds. This observed discrepancy reveals the existence of secondary ice production (SIP) in addition to the primary ice nucleation. However, the importance of SIP relative to primary ice nucleation remains highly un

Gaining a mechanistic understanding of the expansion and maturation program of natural killer (NK) cells will provide opportunities for harnessing their inflammation-inducing and oncolytic capacity for therapeutic purposes. Here, we demonstrated that ID2, a transcriptional regulatory protein constitutively expressed in NK cells, supports NK cell effector maturation by controlling the amplitude and

Protected and spin-polarized transport channels are the hallmark of topological insulators, coming along with an intrinsic strong spin-orbit coupling. Here we identified such corresponding chiral states in epitaxially grown zigzag graphene nanoribbons (zz-GNRs), albeit with an extremely weak spin-orbit interaction. While the bulk of the monolayer zz-GNR is fully suspended across a SiC facet, the l

We used a recently developed classical Density Functional Theory (DFT) method to study the structures, phase transitions, and electrochemical behaviours of two coarse-grained ionic fluid models, in the presence of a perfectly conducting model electrode. Common to both is that the charge of the cationic component is able to approach the electrode interface more closely than the anion charge. This m

The Common Agricultural Policy (CAP) is the largest budget item in the European Union, but varied data reporting hampers holistic analysis. Here we have assembled the first dataset to our knowledge to report individual CAP payments by standardized CAP funding measures and geolocation. We created this dataset by translating, geolocating to the county or province (NUTS3) level, and consistently harm

By changing the institutionalised practices associated with resource distribution, the sharing economy could support sustainable urban transformations. However, its impacts on urban sus-tainability are unknown and contested, and key actors hold different perceptions about them. Understanding how they frame these impacts could help solve conflicts and outline what can be done to influence the devel

This paper aims to synthesize previous user innovation policy proposals into an adapted systems of innovation framework, on which a holistic user innovation policy for the household sector can be based. We identify and review policy proposals made by user innovation researchers and categorize them according to ten key activities in the systems of innovation framework. In the review of 22 publicati

Background Social media is an important and growing part of the lives of the vast majority of the global population, especially in the young. Although still a young and scarce subject, research has revealed that social media has addictive potential. The aim of this cross-sectional study was to explore the associations between problematic use of social media and mental distress, problematic gaming

Clinical reports on early immune dysregulation in acute pancreatitis (AP) are scarce. Herein we investigate the initial temporal development of selected biomarkers. Blood samples were taken at 0–24 and 25–48 h after onsets of AP were acquired. Mean values and temporal intermediate difference (delta-values) of IL-1β, IL-6, IL-8, IL-10, IL-12, IFN-γ and TNF-α were calculated. Differences between sev

Public procurement accounts for a very large share of most economies worldwide. This conceptual article argues that the key to achieving more innovations when pursuing public procurement is to describe problems to be solved or functions to be fulfilled (functional procurement) instead of describing the products to be bought (product procurement). Contracting authorities need to identify the proble

All kinds of public policies are being proposed to address our climate and sustainability challenges, for example, emission standards, substance bans, aviation taxes, energy efficiency labels, and even communication campaigns. However, global carbon dioxide emissions keep going up! Are these policies working? Under what circumstance? And, at what cost to other systems in society? To answer these q

Sialylations are post-translational modifications of proteins and lipids that play important roles in many cellular events, including cell-cell interactions, proliferation, and migration. Tumor cells express high levels of sialic acid (SA), which are often associated with the increased invasive potential in clinical tumors, correlating with poor prognosis. To overcome the lack of natural SA-recept