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BACKGROUND: TNF-α inhibitors are potent anti-inflammatory drugs that have revolutionized the treatment of rheumatoid arthritis (RA). Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) is a non-invasive method to study cartilage quality, in particular the glycosaminoglycan (GAG) content. PURPOSE: To evaluate knee cartilage quality before and after treatment with a TNF-α inhibitor (infliximab) i

De nya sjukpenningreglerna kommer att få en rad konsekvenser inte bara för den enskilde utan också på våra arbetsplatser. De arbetsrättsliga reglerna har inte ändrats, men den verklighet som de verkar i har förändrats radikalt och nya problemställningar dyker upp. Beviljas inte fortsatt sjukpenning ligger det nära till hands att arbetstagaren återkommer till arbetsplatsen och denna ”sjuknärvaro” m

Popular Abstract in English The present thesis investigates ways in which motion is described in Xenophon’s Anabasis, written in the 2nd part of the third century BC. The Anabasis tells the story of the Ten Thousand – the Greek soldiers who marched from Sardis to Babylon, and from there back to the Greek coast of the Black Sea – covering a great variety of motion events. The study examines passageThe thesis compares different prepositions and verbal prefixes denoting direction in Ancient Greek. The corpus covers passages in Xenophon’s Anabasis where such directional elements are used. In this work, it has been examined how the usage of prepositions differs from that of prefixes when they denote a concrete motion in space, what reasons lie behind their usage, and how various directional ele

Sweden, with a high level of political participation and an avant-garde position regarding internet access, broadband and social media penetration in the population, is a critical case for studying social media in relation to political participation. Three types of users – members of political parties, members of interest organizations, and non-members – are interviewed in focus groups about their

The underlying mechanisms responsible for the development of castration-resistant prostate cancer (CRPC) in patients who have undergone androgen deprivation therapy are not fully understood. This is the first study to address whether β2-adrenergic receptor (ADRB2)- mediated signaling may affect CRPC progression in vivo. By immunohistochemical analyses, we observed that low levels of ADRB2 is assoc

BACKGROUND: The early detection of bacterial meningitis is crucial for successful outcome. Heparin-binding protein, a potent inducer of increased vascular permeability, is released from activated neutrophils in severe sepsis.OBJECTIVE: In this study we investigated whether heparin-binding protein levels in cerebrospinal fluid could be used as a diagnostic marker for acute bacterial meningitis.DESI

Cardiac magnetic resonance (CMR) can quantify myocardial infarct (MI) size and myocardium at risk (MaR), enabling assessment of myocardial salvage index (MSI). We assessed how MSI impacts the number of patients needed to reach statistical power in relation to MI size alone and levels of biochemical markers in clinical cardioprotection trials and how scan day affect sample size.

OBJECTIVE: Regular blood pressure control has been advocated for early detection and treatment of patients with hypertension. We aimed to study whether long-term survival rate is related to socioeconomic circumstances and biological factors among middle-aged men with screened new hypertension. METHODS: Of the 22 444 men who attended a general health examination in Malmo, Sweden during 1974-1984, i

When medieval archaeology was formed as an independent academic discipline at Lund University in the middle of the 1960s, town archaeology was a vital part representing one of the orders in feudal society. It was established as a recognizable discourse and a major arena for excavating medieval archaeology. The article deals with the following issues: What kind of epistemological currents have infl

Lords and peasants : on jurisdiction in some baronies in Småland in the seventeenth century