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Protein Kinase Inhibition in Late Cerebral Ischemia after Subarachnoid Hemorrhage
The cerebral ischemia that occur after a subarachnoid hemorrhage (SAH) often results in death or severe disability and is a significant cause of stroke. Our hypothesis is that cerebral ischemia leads to pathophysiological receptor changes on the vascular smooth muscle cells. The changes may lead to a stronger vasoconstriction than normal in response to endogenous ligands. We are focusing on the en
Selective catalytic reduction of NOx: a mathematical model for poison accumulation and conversion performance
A common control technique for limiting nitrogen oxide emissions is selective catalytic reduction (SCR) of NO, with NH,. The lifetime of the catalyst, which has a critical role in overall SCR system economics, is, however, limited due to deactivation by poisoning. A two-dimensional model was developed to describe poison accumulation and activity of an SCR catalyst. The model that has no adjustable
Assessment of changes in endometrial and subendometrial volume and vascularity during the normal menstrual cycle using three-dimensional power Doppler ultrasound.
Research and development of radiation therapy in clinical routines
In an investigation conducted by the Swedish Cancer Society. the present status, critical issues and future aspects and potentials were described by expert group for each of nine major areas of radiation therapy research. In this report, research and development in radiation therapy clinical routines is described. The terms research, development, quality assurance, quality control and clinical rou
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This paper treets the acquisition, variation and historical change in the use of the article with kinship names in Italian, or more precisely, the Florentine variety of Italian. The development in acquisition data and historical texts is compared regarding the use of the definitive article together with kinship nouns. The children studied in this paper classify DPs in non-target-like ways apparent
Characteristics of snowmelt induced peak flows in a small northern basin
One Hour Photo (2002) + John Q (2002) + Changing Lanes (2002) (film review)
Studentdatorprojektet utvärderat: Hård kritik mot pilotförsök
Artikel om kritiken av Lunds universitets studentdatorprojekt från utvärderaren Conny Svenning.
Causal Facts
Popular Abstract in Swedish Vad är ett orsakssamband? Och vad är en orsak? Författaren hävdar att orsakssamband är lika verkliga och lokala som dess orsaker och effekter. Denna position är diametralt motsatt synen att orsakssamband i den mån de alls kan sägas finnas är instanser av lagbundenheter; en syn som (med viss orätt) tillskrivs David Hume, och som sedan dennes Treatise (1739) under långa tThe thesis addresses the nature of causation. It is argued that causation exists and is as local as its causes and effects. As a consequence, the position advocated is contrary to the as yet prevailing view that no 'causal tie' between cause and effect exists. Moreover, it is suggested that this tie can be perceived. The essay attempts to elucidate the nature of causes, effects, and causal mechani
Fatality of Future Coronary Events Is Related to Inflammation-Sensitive Plasma Proteins. A Population-Based Prospective Cohort Study.
Explaining the Collapse: A Review of Four Approaches to the Breakdown of the Soviet Union
MCHF calculations of autoionization widths in two- and three-electron systems
We present calculations of autoionization widths using a fully numerical multiconfigurational Hartree-Fock method (MCHF). Energy positions and autoionization rates are given for several doubly-excited states lying below the n = 2 threshold in He I and H-. Particular attention is given to orthogonality considerations in the computation of the autoionization widths. The method is extended to the 1s2
Konsum Eken. Exempel på utvecklingen av ett nytt personalkoncept
The Geneva-Copenhagen survey of the Solar neighbourhood. Ages, metallicities, and kinematic properties of ∼14 000 F and G dwarfs
We present and discuss new determinations of metallicity, rotation, age,kinematics, and Galactic orbits for a complete, magnitude-limited, andkinematically unbiased sample of 16 682 nearby F and G dwarf stars. Our∼63 000 new, accurate radial-velocity observations for nearly 13 500stars allow identification of most of the binary stars in the sampleand, together with published uvbyβ photometry, Hipp
Size and Power of the RESET Test as Applied to Systems of Equations: A Bootstrap Approach
The size and power of various generalization of the RESET test for functional misspecification are investigated, using the “Bootsrap critical values”, in systems ranging from one to ten equations. The properties of 8 versions of the test are studied using Monte Carlo methods. The results are then compared with another study of Shukur and Edgerton (2002), in which they used the asymptotic critical
Surface Proteins of Streptococcus agalactiae and Related Proteins in Other Bacterial Pathogens.
Streptococcus agalactiae (group B Streptococcus) is the major cause of invasive bacterial disease, including meningitis, in the neonatal period. Although prophylactic measures have contributed to a substantial reduction in the number of infections, development of a vaccine remains an important goal. While much work in this field has focused on the S. agalactiae polysaccharide capsule, which is an
The use of a pharmacophore model for identification of novel ligands for the benzodiazepine binding site of the GABA(A) receptor
A Catalyst pharmacophore model has been developed for the benzodiazepine site within the GABA(A) receptor complex. The model is based on a pharmacophore model originally proposed by Cook and co-workers (Drug Des. Discovery 1995, 12, 193-248) and further developed by Kahnberg et al. (J. Med. Chem. 2002,45, 4188-4201). The Catalyst pharmacophore model has been validated by using a series of flavonoi
Distribution of preproatrial natriuretic peptide mRNA in rat brain detected by in situ hybridization of DNA oligonucleotides: enrichment in hypothalamic and limbic regions
The expression and distribution of mRNA encoding preproatrial natriuretic peptide (ppANP) in rat brain has been investigated by in situ hybridization of two 35S-labeled synthetic DNA oligonucleotides, based on a cDNA clone sequence that encodes rat ppANP. The highest relative concentrations of ppANP mRNA were detected in the medial preoptic hypothalamic nucleus ("anteroventral/third ventricle regi
Susceptibility factors and DNA adducts in peripheral blood mononuclear cells of aluminium smelter workers exposed to polycyclic aromatic hydrocarbons
Formation of DNA adducts as a result of exposure to polycyclic aromatic hydrocarbons (PAH) was studied in 98 potroom workers from an aluminium smelting plant and in 55 blue-collar workers without occupational PAH exposure. DNA from peripheral blood mononuclear cells (PBMC) was used for quantitation of individual PAH-DNA adducts by P-32-postlabelling/high performance liquid chromatography (HPLC) an