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Misfolding and aggregation of amyloid β (Aβ) are key features of Alzheimer's disease (AD) pathogenesis, but the molecular events controlling this process are not known in detail. In vivo, Aβ aggregation and plaque formation occur in the interstitial fluid of the brain extracellular matrix. This fluid communicates freely with cerebrospinal fluid (CSF). Here, we examined the effect of human CSF on A

Surfactants have been the basis for applications in several industrial sectors for a long time. However, fundamental research was 50 years ago still limited to a small number of academic groups and even basic aspects were controversial. The field has since undergone an enormous expansion and the improved understanding has laid the basis of numerous new products as well as been the basis of importa

Finite-element programs can be used for designing columns and their bracing systems. It is well known, however, that the output obtained from such programs is highly dependent upon the input (such as imperfections and stiffness properties). In the present study, the effects of imperfections on the predicted strength and stiffness requirements of steel columns and of their bracing systems are inves

The peroxisome proliferator-activated receptor gamma (PPARgamma), a member of the nuclear hormone receptor superfamily, is essential for adipocyte differentiation and glucose homeostasis. PPARgamma has been found recently to regulate macrophage activation in response to mitogens and inflammation. Our study shows PPARgamma to be preferentially expressed in the nuclei of resting T cells and to incre

In this study we have compared the interaction of human MHC class I molecules with IgG heavy chain (HC) binding protein (BiP), calnexin, calreticulin, tapasin and TAP in beta(2)-microglobulin (beta(2)m)- or TAP-deficient cells, as well as in wild-type B-LCL cells. Distinct differences between the association of HC and these endoplasmic reticulum (ER) proteins were found in the three cell lines. In

The growth hormone/insulin-like growth factor (IGF) axis can be manipulated in animal models to promote longevity, and IGF-related proteins including IGF-I and IGF-binding protein-3 (IGFBP-3) have also been implicated in risk of human diseases including cardiovascular diseases, diabetes, and cancer. Through genomewide association study of up to 30 884 adults of European ancestry from 21 studies, w

The text "A Kind of Friend" is a written abstract about the video essay with the sam name

E-learning tools are becoming more advanced as Web 2.0 and the participatory Internet evolves. This paper discusses the need for a concrete pedagogical foundation on how to best use E-Learning tools. By examining some of the tools that are available now, we discuss what is suitable and what could be inappropriate. The significance of the traditional didactic triangle is reviewed and a new twist mi

Lute suites by J.S Bach recorded on the 11-string alto guitar

Works for flute viola and guitar performed by Terje Thiwång, flute, Torbjörn Helander, viola and Stefan Östersjö guitar. Music by Kent Olofsson, Kay Holmquist, Rolf Martinsson, André Chini and Fredrik Österling

Works for guitar and electronics by Kent Olofsson, Åke Parmerud, Tommy Zwedberg, Kent Nyman and Agustín Fernandez

Works for guitar and chamber ensemble, soloist Stefan Östersjö with Ensemble Ars Nova and Gageego, conductors Harald Eikaas and Pierre André Valade

A discussion on the practice of opera improvisation as a means to go in dialogue with music and performance culture in the western classical field, inspired by perspectives from cultural theory, suggesting notions of intertextuality and interperformativity.

Concerto for guitarist and orchestra, soloist Stefan Östersjö with the Gothenburg Symphony Orchestra, conductor Mario Venzago

A double CD box with the complete works for guitar solo of Per Nørgård

An article about the English sound poet Bob Cobbing and the work he did at the Text Sound Festivals in Stockholm.

Repetition Repeats all Other Repetitions is a composition for 10-string guitar and electronics by Henrik Frisk. This is a CD release of the first version of the piece.