The effect of continuous and intermittent ethanol exposure on the phospholipid composition of Neuroblastoma x Glioma (NG 108-15) cell membranes was investigated. The cells were treated with ethanol for three weeks. Continuous ethanol exposure (150 mM) produced an increase (27%) in the amount of phosphatidylcholine, whereas intermittent ethanol treatment (150 mM) induced a 22% reduction of this lip

Decreased levels of the anti-inflammatory Clara Cell Protein 16 (CC16) are found in intermittent allergic rhinitis (IAR) and asthma. In asthma this decrease has been associated with hyperreactivity and the A38G single nucleotide polymorphism (SNP). The aim of this study was to examine if IAR is associated with signs and symptoms of rhinitis and the A38G SNP. Nasal fluid CC16 was analyzed in 20 pat

Popular Abstract in Swedish Avhandlingens syfte är att undersöka energianvändningen och miljöpåverkan från bostäder. Sju autentiska byggnader byggda under 1990-talet i Sverige har studerats. De är analyserade med avseende på energianvändningen och miljöpåverkan under deras livscykel: tillverkning av byggnadsmaterial, transport av byggnadsmaterial och -komponenter till byggarbetsplats, uppförande, The objective of this thesis is to investigate the energy use and environmental impact of residential buildings. Seven authentic buildings built in the 1990s in Sweden are investigated. They are analysed according to energy use and environmental impact during their life cycle: manufacture of building materials, transport of building materials and components to the building site, erection to a buil

Background. Third trimester fetal death is a common problem in Mozambique, occurring in approximately 5% of parturient women. Objective. To elucidate the magnitude of the gestational diabetes mellitus problem, and to estimate its prevalence in a group of women with unexplained late fetal deaths and in women with live fetuses (referents). Methods. An incident case-referent study of 109 pregnant Moz

Background: A majority of patients with pancreatic cancer have obstructive jaundice and diabetes with skeletal muscle insulin resistance. Surgery for these patients is associated with significant morbidity. Uncoupling protein 2 (UCP2) has been proposed to regulate energy expenditure and promote liver vulnerability. The effects of obstructive jaundice on muscle glucose metabolism and expression of

In this paper the first resonant photoemission and partial electron yield studies of free clusters are presented. The resonant photoemission spectra of free argon clusters have been recorded with excitation energies determined from the cluster X-ray absorption spectrum near the Ar 2p ionization threshold. The decay of 2p(-1)4s and 2p(-1)3d cluster surface and "bulk" excited states has been investi

The efficiency of numerical time-stepping methods for dynamical systems is greatly enhanced by automatic time step variation. In this paper we present and discuss three different approaches to step size selection: (i) control theory (to keep the error in check); (ii) signal processing (to produce smooth step size sequences and improve computational stability); and (iii) adaptivity, in the sense th

Attention-deficit/hyperactivity disorder (ADHD) is related to an attenuated and dysfunctional dopamine system. Normally, a high extracellular dopamine level yields a tonic dopaminergic input that down-regulates stimuli-evoked phasic dopamine responses through autoreceptors. Abnormally low tonic extracellular dopamine in ADHD up-regulates the autoreceptors so that stimuli-evoked phasic dopamine is

I rapporten presenteras mätningarn, som har gjorts under perioden december 1987 till april 1988, av Nox-halten i luften i omgivningen av avgasutsläpp från en naturgaseldad villapanna. Bl.a. redovisas hur olika vindhastigheter och vindriktningar inverkar på Nox-halten i pannans omgivning.

Patients with Fanconi anemia (FA) are prone to develop malignancies at an early age. Besides hematologic malignancies, squamous cell carcinomas in the anogenital region and head and neck are also frequently found in these patients. The aim of this study was to generate a panel of head and neck squamous cell carcinoma (HNSCC) cell lines and xenografts of FA HNSCC, and to characterize these cell lin

The method of normal form originating from the work of A.D. Brjuno has been used in the analysis of two-degrees-of-freedom discrete systems with eccentric follower force. Various types of external and internal damping has been taken into consideration. The program NORFOR2 is compared with program BIFOR2, which is based on Hopf Bifurcation, as to the capacity and speed in solving non-linear, non-co

Although free radicals have been suggested to contribute to ischemic brain damage for more than 10 years, it is not until quite recently that convincing evidence has been presented for their involvement in both sustained and transient ischemia. The hypothesis is examined against current knowledge of free radical chemistry, as it applies to biological systems, and of cellular iron metabolism. It is

Exposure to methylene chloride produced a time and concentration related increase in liver weight. The effect was more prominent in female mice than in male. The activity of plasma butyrylcholinesterase (BuChE) increased even more than the liver weight at corresponding exposures, but only in the males. Fatty infiltration was noticeable after exposure to 75 p.p.m. and was more prominent in the fema

We investigate the three-neutrino mixing scheme for solving the atmospheric and LSND anomalies. We find the region in the parameter space that provides a good fit to the LSND and the SK atmospheric data, taking into account the CHOOZ constraint. We demonstrate that the goodness of this fit is comparable to that of the conventional fit to the solar and atmospheric data. Large values of the LSND ang

Elimination of all animal material during both the derivation and long-term culture of human embryonic stem cells (hESCs) is necessary prior to future application of hESCs in clinical cell therapy. The potential consequences of transplanting xeno-contaminated hESCs into patients, such as an increased risk of graft rejection [STEM CELLS 2006;24:221229] and the potential transfer of nonhuman pathoge

This review summarizes experimental findings that highlight the complex roles of the immune system in atherogenesis. Immune activation can have either proatherogenic or atheroprotective effects. Immune-modulation therapy via an active or passive immunization strategy aims to exploit the atheroprotective aspects of the immune system to modulate atherosclerosis. Several experimental studies have dem