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Background: The effect of pneumococcal conjugate vaccines (PCV) on invasive pneumococcal disease is frequently reported, but the impact on upper respiratory tract infections in a clinical setting is less documented. Our aim in this 5-year observational study was to investigate serotype changes in a large number of Streptococcus pneumoniae upper respiratory tract isolates following sequential intro

Background: We here study antibodies against phosphorylcholine (anti-PC) which we reported to be inversely associated with atherosclerosis, cardiovascular disease (CVD), and autoimmune conditions. In previous studies, we determined that this inverse association is more pronounced at low levels with high risk and at high levels, with decreased risk. We compare individuals from Kitava, New Guinea (w

Familial aggregation (clustering) of venous thromboembolism (VTE) is the clustering of VTE within a family. Though several genes, such as antithrombin, protein C, protein S, factor V, and prothrombin are associated with the familial clustering of VTE, these loci only partially explain the familial aggregation of VTE. The epidemiology of the familial aggregation of VTE exhibits typical characterist

In this paper the characteristics of the primary breakup of a liquid jet is analyzed numerically. We applied the Volumes of Fluids (VOF) approach utilizing the Direction Averaged Curvature (DAC) model, to estimate the interface curvature, and the Direction Averaged Normal (DAN) model, to propagate the interface. While being used for the first time to predict liquid atomization, this methodology sh

Background: Coronary heart disease (CHD) and myocardial infarction (MI) are associated with neighborhood-level socioeconomic status (SES). Statins are important drugs for secondary prevention of MI. However, no study has determined whether neighborhood-level SES is associated with statin medication in MI patients. We aimed to determine whether there is a difference in statin medication rate in MI

In addition to brain injury stroke patients often suffer gastrointestinal complications. Neuroimmune interactions involving galectin-3, released from microglia in the brain, mediates the post-stroke pro-inflammatory response. We investigated possible consequences of stroke on the enteric nervous system and the involvement of galectin-3. We show that permanent middle cerebral artery occlusion (pMCA

Much debate has revolved around nutrient limitation in estuaries. A common view today is that nitrogen (N) and phosphorus (P) act as co-limiting nutrients, both for processes carried out by phytoplankton and by bacterioplankton, although recent studies show that also carbon (C) may control estuarine bacterioplankton, even in systems with large inputs of terrestrial organic matter (tOM). We conduct

Construction work is physically demanding and often associated with bodily pain. This article presents a study of construction workers’ practices of using and relating to their bodies at work through an agential realist framework for analysing the (re)configuration of the workers’ embodied subjectivity. The analysis draws on interviews with 32 Danish construction workers as well as brief observati

During the 90ies, ISO TC92 SC1 started the development of full-scale tests for facades based upon an international review. The work resulted in two standards namely ISO 13785 part 1 and part 2. The work was performed in WG7 and a substantial input from international experts was given. The paper gives a short historical update on the development but also includes a short overview of the major type

This study aims to give an overview over different reaction-to-fire prediction models developed over the last decades by finding similarities and differences between models, as well as identifying their robustness in scaling. The models have been divided into four categories - empirical, thermal, polynomial and comprehensive - depending on how pyrolysis is modelled. Empirical models extrapolate be

Fires in enclosures equipped with mechanical ventilation remain one of the key issues for fire safety assessment in multifamily homes and industries. Therefore, a wide variation of methods for preventing smoke spread through the ventilation system exist and are applied, in performance-based designs. Through the use of the heating, ventilation and air conditioning (HVAC) model in the fire dynamics

This work has been made as a thesis for a BSc degree in Fire Protection Engineering at Lund University. The work has been supported and funded by ESS AB, European Spallation Source, in Lund. ESS AB is a publicly held company, owned by Sweden and Denmark as host countries. These host countries, together with at least 17 other European countries, will build and establish a multidisciplinary research

The characteristics of smoke are highly dependent on the materials undergoing thermal decomposition and the environment in which this decomposition takes place. With the rising complexity in dedicated fire simulation tools, there is a need for increased information on the composition and properties of smoke in order to develop/validate and extend the fire safety engineering community's smoke and v

Traditionally in fire modelling, a solid fuel has been assumed to ignite when the solids surface reaches a specific temperature or when the heat flux upon the solid reaches a critical level. Although these approaches of determining ignition for the condensed phase are practical, ignoring the gas phase conditions may lead to incorrect assumptions regarding material safety. A more 'physical' explana

It has been shown in previous studies that the current standard used to fire test interior materials in civilian and military vehicles, ISO 3795 (FMVSS 302), has led to a low level of fire safety of interior materials in civilian vehicles. The purpose of this study was to evaluate the fire safety of interior materials in military vehicles. The aim was to suggest a fire test method to be used on in