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Effects of calcium, dairy product, and vitamin D supplementation on bone mass accrual and body composition in 10-12-y-old girls: a 2-y randomized trial

BACKGROUND: Little is known about the relative effectiveness of calcium supplementation from food or pills with or without vitamin D supplementation for bone mass accrual during the rapid growth period. OBJECTIVE: The purpose was to examine the effects of both food-based and pill supplements of calcium and vitamin D on bone mass and body composition in girls aged 10-12 y. DESIGN: This placebo-cont

Hypoxia-induced phenotypic modulation of human neuroblastoma cells

Popular Abstract in Swedish POPULÄRVETENSKAPLIG SAMMANFATTNING Introduktion Cancer uppstår när en cell i kroppen börjar dela sig okontrollerat, varmed det sker en onaturlig ansamling av celler ? tumörbildning. Solida tumörer t ex bröst- och prostatacancer är till skillnad från ickesolida tumörer som blodcancer/leukemi ofta dåligt försedda med syre på grund av långa avstånd mellan tumörceller ochNeuroblastoma is a childhood tumour derived from cells of the sympathetic nervous system, which are arrested at low differentiation stages. Low differentiation stage and high tumour stage correlate to poor outcome. In earlier studies we have found that hypoxia induces dedifferentiation of neuroblastoma cells, which implies that hypoxia evokes a more aggressive phenotype. Here we employ microarray

Computationally Efficient Time-Varying ISAR Imaging

By exploiting the relative motion between the target and the radar, high-resolution images of moving targets can be produced using inverse synthetic aperture radar (ISAR). Recent studies have shown that accurate ISAR images can be obtained using the non-parametric high-resolution Capon and APES spectral estimators. In this paper, we propose a computationally efficient time-updating of the two-dime

Ur Hysteran

Om kvinnlighet och hysteri utifrån den franske psykoanalytikern Luce Irigarays teorier.

Appetite suppression through delayed fat digestion

High-fat diets are often associated with greater caloric intake and weight gain. Since satiety during fat intake is induced by fat in the intestine we investigated the efficiency of a lipid compound that retards fat digestion to regulate fat intake. We found this compound to reduce high-fat food intake, body weight and blood lipids in Sprague-Dawley rats, without causing steatorrhea. The absence o

The impact of canopy exchange on differences observed between atmospheric deposition and throughfall fluxes

To study the impact of canopy exchange on differences observed between atmospheric deposition and throughfall fluxes, several-held experiments were performed at the Speulder forest in The Netherlands. Relevant information was obtained by (i) measuring open-field precipitation and throughfall fluxes with different time resolutions, using two canopy exchange models, (ii) by comparing results from su

4-aminobiphenyl-hemoglobin adducts and risk of smoking-related disease in never smokers and former smokers in the European prospective investigation into cancer and nutrition prospective study

The aim of this study was to evaluate whether biomarkers of environmental tobacco smoke exposure [i.e, 4-aminobiphenyl-hemoglobin (4-ABP-Hb) adducts] were predictive of the risk of tobacco-related cancers and diseases. We did a case control study nested within the European Prospective Investigation into Cancer and Nutrition, involving 190 controls and 149 cases (incident cancer of the lung, bladde

Proliferation, Invasion and p16 Localisation in Malignancies

Popular Abstract in Swedish Okontrollerad proliferation och invasion är två viktiga egenskaper i tumörutveckling och tumörprogression. Tidigare studier har visat att invaderande tumörceller i kolorektalcancer har låg proliferation parallellt med en uppreglering av tumörsuppressorn p16. Vi undersökte p16-uttrycket och proliferation i basalcellscancer och skivepitelcancer i huden, tumörer som är lokUncontrolled proliferation and invasion are two characteristics in tumour development and progression. Previous studies have shown that invading tumour cells in colorectal cancer have low proliferation in parallel to upregulation of the tumour suppressor p16. We set out to detail the p16 expression and proliferation in basal cell carcinoma and squamous cell carcinoma of the skin, tumours that are

Reversal of lethal citrate intoxication by intravenous infusion of calcium. An experimental study in pigs

Intravenous infusions of 750 and 1000 ml 2.2% sodium citrate were given over a 60 min period to 17 pigs to study its effect on aortic pressure, electrocardiogram, ionised calcium, and citrate clearance. In group 1 (seven pigs) the animals did not receive calcium and the median survival time was 30 min (range 20-70 min). In groups 2 and 3 (five in each group) the pigs were treated with calcium chlo