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The therapeutic potential of glial cell line-derived neurotrophic factor ( GDNF) for Parkinson's disease is likely to depend on sustained delivery of the appropriate amount to the target areas. Recombinant adeno-associated viral vectors ( rAAVs) expressing GDNF may be a suitable delivery system for this purpose. The aim of this study was to define a sustained level of GDNF that does not affect the

OBJECTIVE: The purpose of this study was to compare the usefulness of the Nottingham Health Profile (NHP) and the Short-Form 36 Health Survey (SF-36) as general outcome measures after vascular intervention for lower limb ischemia with respect to patients' quality of life, on the basis of validity, reliability, and responsiveness analyses. Patients and Methods: Eighty patients, 40 with claudication

In the process of constructing a confidence region induced by the Wilcoxon two-sample test ties always appear. We show that, for various ways of handling ties, the confidence region will be an interval.

This paper describes a development process concerning the active involvement of staff of different professions in developing and implementing methods for assessment of activities of daily living (ADL) in home-based geriatric rehabilitation. Although a variety of established ADL instruments exist, at the time for this study no I-ADL (Instrumental Activities of Daily Living) instrument suitable for

The objective of this study was the investigation of the maximal potential donor pool and causes of non-realized organ donation. On-site retrospective medical-record review was performed for all cases of patient death (n=1608) occurring in 1999 at 34 (83% of all) intensive care units (ICUs) in the region of the transplant center in Prague, Czech Republic. Two hundred and eighty-eight (18%) patient

This thesis concerns the usage of large pollen databases and their application to mapping and modelling past vegetation. Maps of past taxon distributions are generated and classification techniques are used to compile maps of past woodland types. These visualisations of pollen data have applications in forest ecology and in modelling the impacts of climate change. Maps of the distribution limits o

I vilken mening kan vi idag tala om en "evangelikal" exegetik? Vad innebär det idag att bedriva exegetik utifrån en evangelikal utgångspunkt och teologi? Är evangelikal exegetik i själva verket ett uttryck för en svunnen tid och gamla polariseringar? Finns det idag nya fronter i bibelsynsfrågorna? Detta är några av de brännande frågor som behandlas av de åtta bidragsgivarna.

Among all noise sources present in wireline transmission systems we focus on one special type: narrowband radio frequency interference generated by radio amateurs (HAM) and broadcast radio stations. This disturbance, characterized by high power and narrow bandwidth, has the potential of overloading the receiver's analog-to-digital converter (ADC). Once the ADC is in saturation, any countermeasure

Objective: To assess the clinical value of serial single photon-emission computed tomographic (SPECT) measurements after aneurysmal subarachnoid hemorrhage (SAH). Methods: Thirty-two patients were studied prospectively during the first 26 days after SAH with repeated SPELT measurements; clinical examinations, and transcranial Doppler recordings. Time trends were analyzed with a general linear mode

We complete here our work on isospin violation in the K -> 3 pi system. We first calculate K -> 2 pi to the same order as we did K -> 3 pi in papers I and II of this series. This adds the effects of order G(27)p(2)(m(u) - m(d)) and G(27)p(2)e(2) to earlier work. We calculate also the lowest order bremsstrahlung contributions, K -> 2 pi gamma, 3 pi gamma. With these and our earlier results we perfo

In this paper we have conducted a systematic study of the photoelectron diffraction (PED) effects from the 3C-SiC(0 0 1)-c(4 x 2) surface by means of multiple-scattering calculations. Two models have been proposed to describe this surface: alternately up and down dimers (AUDD) [P. Soukiassian, F. Semond, L. Douillard, A. Mayne, G. Djuradin, L. Pizzagalli, C. Joachim, Phys. Rev. Lett. 78 (1997) 907

Popular Abstract in Swedish Denna doktorsavhandling i Rättssociologi handlar om barns rättigheter och barnarbete i Paraguay. Problematiken kring barnarbete i Paraguay är central för avhandlingen och författaren har undersökt samt beskrivit de rättsliga ideal som är tänkta att upprätthålla och stärka det rättsliga skyddet för barns rättigheter. De rättsliga idealen kontrasteras sedemera mot den norThe present study is composed of eight chapters relating to children's rights and child labor activity in the Republic of Paraguay. The problem of child labor in Paraguay is central for this study and the legal ideals that are intended to uphold and strengthen the rights of the child are described and contrasted with the present normative reality in which the children work and live. The discrepanc

Caloplaca erecta Arup & H. Mayrhofer is described here as new to science. It belongs to a group of dwarf-fruticose species, but cannot be accommodated within any of the known species of that group. It forms dense cushions of erect lobes on siliceous rocks, and is known only from Mt. Maungatua. This is the second dwarf-fruticose species of Caloplaca in the Australasian area, in addition to C. c

The paper describes the approach used at the Department of Automatic Control at Lund Institute of Technology to maintain a high level of practical laboratory experiments. The Department integrates laboratory experiments into its control courses. If the laboratory exercises are properly organized and the student volume is sufficiently large, it is possible to combine a high level of practical labor

A first clinical evaluation has been made of the performance of a newly devised immunofluorometric assay for measuring plasma concentrations of activated protein C (APC) in complex with protein C inhibitor (PCI). The method was compared with testing for other markers of hypercoagulability in a case-control study comprising 123 patients with clinical suspicion of deep vein thrombosis (DVT). The dia