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Expanded Codon Technology for Producing Phosphorylated Enamel Matrix Protein

Amelogenin, a critical protein in enamel formation, self-assembles into supramolecular structure that guide hydroxyapatite (HAP) crystal growth that is essential for the development of strong and healthy enamel. Phosphorylation of amelogenin at Ser-16 plays a pivotal role in modulating its self-assembly and functional properties, impacting the overall enamel biomineralization process. This post-tr

Interconnecting Multiple FPGAs for Distributed Machine Learning Inference

Machine learning has been growing in popularity for many years now and is currently popular among both businesses and private individuals. Running machine learning models takes a lot of computational resources, which means a large amount of energy is consumed. The aim of this thesis is to investigate the usage of machine learning model specific hardware on Field Programmable Gate Arrays (FPGAs) a

Characterisation of the Plasmid Encoded AdeRS and AdeABC Variants Involved in Antibiotic Resistance

Antibiotic resistance is a global concern and is promoted by various types of bacterial efflux systems. One known efflux system expressed by the Acinetobacter genus is the chromosomally encoded AdeABC pump which works in conjunction with the regulatory system AdeRS. Recently, plasmid encoded variants of the adeRS and adeABC have been identified and it is thought that these may pose similar or high

Mänsklig Faktor i Cybersäkerhet: En undersökning om hur utbildningen för cybersäkerhet ser ut bland medelstora och stora företag

Den tekniska utvecklingen tillåter företagen att implementera nya lösningar i sina verksamheter, men den låter även cyberangripare utveckla nya metoder för att angripa företagen. En rad olika metoder bygger på att lura den enskilda anställda i företaget att dela känsliga data med angriparen utan att de själva vet om det. Människan har även beskrivits som den “svaga länken” i cybersäkerhet, efterso

How does education influence the cognitive mechanism used in the entrepreneurial ideation phase?

Entrepreneurship is essential to accelerate entrepreneurial innovation and economic growth. Brilliant ideas do not only arise from the Eureka moment but the founder's talent and creativity have a large cooperation in this process. There are many factors that trigger the founder's creativity and can lead to successful entrepreneurship. This paper aims to study the relationship between the c

Metoder för hantering av tvärsnittskorrelation

This study examines how three different methods for addressing cross-sectional dependency can affect the regression results. By ignoring the problem, using a two-way fixed effects model and using Common Correlated Effects (CCE), three regressions are run to answer the research question. In order to conduct this analysis, a growth model is specified and consists of the following explanatory variabl

Vård av unga med könsdysfori och unga med intersexvariationer - En komparativ WPR-analys

This paper aims to investigate the policies in two documents from the National Board of Social Affairs and Health regarding healthcare for transgender youth and people with intersex variations. Using Bacchis method of analysis ”What's the problem represented to be?” as well as Michel Foucault's theory of biopower and Judith Butler’s theory of the heterosexual matrix, we examined the assump

The impact of angular momentum on the stellar mass and stellar density of galaxies

The current work aims to investigate the impact of angular momentum in galaxy formation especially in the coevolution of the stellar central density (Σ⋆,1.2kpc) and total stellar mass (M⋆). This is achieved by tracing the histories of three simulated halos where the specific angular momentum is altered by modifying the initial conditions of the Lagrangian patch of baryons. The analysis consists of

“Det behöver inte vara orgasm, det kan vara njutning överlag!” En intervjustudie om äldre kvinnors upplevelse av sexualitet och sexuell tillfredsställelse

Individers förhållningssätt och tillfredsställelse rörande sin sexualitet har visat sig hänga nära samman med upplevt mående och hälsa. Äldre kvinnors upplevelse av sin sexualitet är ett relativt outforskat område, speciellt i en svensk kontext. Mot bakgrund av detta var syftet med denna studie att skapa en fördjupad förståelse och kunskap kring 65-80 åriga kvinnors upplevelse av sexualitet och seIndividuals' attitudes and satisfaction regarding their sexuality have been shown to be closely related to perceived well-being and health. Older women's experience of their sexuality is a relatively unexplored area, especially in a Swedish context. In light of this, the aim of this study was to create a deeper understanding and knowledge of 65-80 year old women's experience of sexuali

Controlled Condensation in a Fixed Dome Camera Using Active Cooling

This thesis investigates the possibilities of preventing condensation from forming in the optical field of view in surveillance cameras with a dome through active cooling. The forming of condensation has been a challenge in these cameras, which can affect the quality of the image. By implementing different Peltier modules and varying their placement and power, this thesis has aimed to evaluate the

Investigation of Interaction between Aquaporin 5 and Cytoplasmic Proteins CLIP2 and β-catenin

In all living organisms, proteins which transport water and other small solutes across the membrane exist and are known as aquaporins. Aquaporins consist out of four monomers, forming a homo-tetramer with a substrate conducting channel in each monomer. Aquaporins can be regulated by either gating or trafficking, which allows the cell to control the permeability of the membrane. Aquaporin 5 is one

Confronting Entrepreneurial Stress - Unpacking the Coping Strategies of Entrepreneurs

The recent surge in entrepreneurship can be attributed, in part, to the perceived advantages it offers, such as independence and flexibility, which have motivated many to pursue this career path. Beneath the surface, however, the entrepreneurial landscape is filled with frustrations and challenges that affect the emotional well-being of business owners. Understanding these challenges and identifyi

Method Development for Droplet and Particle Size Distribution Measurements using Laser Diffraction

Metodutveckling för Mätning av Dropp- och Partikelstorleksfördelning med hjälp av Laserdiffraktion Partiklar finns i princip överallt runtomkring oss, och har en stor betydelse inom många industrier. Partikelstorleken i målarfärg avgör dess kvalitet, partiklar i miljön påverkar vår hälsa, och partikelstorleken i läkemedel påverkar dess effektivitet och stabilitet, för att nämna några exempel. FokuThis degree project aims to develop standard methods for determination of the size distribution in different samples using laser diffraction, as well as to create methodologies for development of new methods for unknown samples. The size distribution is crucial to understand for pharmaceutical products since it affects properties such as the stability and bioavailability of the product. A way to

Floating Community - Seasteading as a Solution to Navigate Rising Seas and Growing Cities

Considering the looming threat of rising sea levels and the imminent flooding of many coastal cities by 2050, numerous initiatives are underway to strengthen these regions with various flood protection programs and barriers. However, there might be another solution than just building barriers around our cities. What if, rather than building next to the water, we envision a lifestyle where we inhab

Structure Affinity Relationship Study of Macrocyclic Peptide Scaffold Binding to PSD-95

Acute ischemic stroke is one of the major causes of death and disability worldwide. New neuroprotective strategies have emerged, with the postsynaptic density protein 95 (PSD-95) identified as a promising target. PSD-95 plays a crucial role in controlling downstream NMDA receptors and neuronal death. Consequently, therapies targeting PSD-95 could mitigate stroke damage while promoting brain protec

Identification of novel macrocyclic inhibitors of PSD-95 using tailored mRNA encoded libraries

Macrocyclic peptides are promising therapeutic modalities due to their ability to target protein-protein interactions (PPIs) with high specificity and affinity. In contrast to their linear analogues, macrocycles are conformationally constrained and the lack of N- and C-terminal make them more resistant to metabolic degradation. Advances in de novo peptide drug discovery, such as the Random non-sta

Prognostic impact of CD163 and CD11c in B cell lymphomas

Diffuse large B cell lymphoma (DLBCL) and mantle cell lymphoma (MCL) are aggressive non-Hodgkin lymphomas often diagnosed at advanced stages in elderly patients. Current tools for patient stratification do not sufficiently identify patient groups resistant to treatment. The presence of CD11c+ cells has previously been associated with pro-inflammatory tumour-immune microenvironment (TIME), while CD

Att förstå prokrastinering: En kvantitativ undersökning av studenters livstillfredsställelse och vardagsbeteenden

Denna studie syftade till att undersöka samband mellan prokrastinering, rutin, livstillfredsställelse, inre motivation och fysisk aktivitet hos studenter på Lunds Universitet. Vidare undersöktes om det går att predicera både prokrastinering och livstillfredsställelse med resterande faktorer, och sist utforskades det om det fanns någon skillnad i resultaten mellan de olika fakulteterna vid universiThis study aimed to investigate the relationships between procrastination, routine, quality of life, intrinsic motivation, and physical activity among students at Lund University. Furthermore, the study examined whether procrastination and quality of life could be predicted by the other factors, and finally explored if there were any differences in the results between the various faculties at the

När kris för en blir möjlighet för en annan

Examensarbetets titel: När kris för en blir möjlighet för en annan Seminariedatum: 30 maj 2024 Ämne/kurs: FEKH69, Examensarbete i redovisning på kandidatnivå, 15 högskolepoäng Författare: Anna Gustafsson, Ebba Fröberg och Tilda Loudd Handledare: Mattias Haraldsson Fem nyckelord: Finansiell kommunikation, kriskommunikation, accountteori, legitimitet, krig Forskningsfråga: Hur väljer företag som påv