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Difficulties in diagnostics of lung tumours in biopsies : An interpathologist concordance study evaluating the international diagnostic guidelines

Aims: Accurate and reliable diagnosis is essential for lung cancer treatment. The study aim was to investigate interpathologist diagnostic concordance for pulmonary tumours according to WHO diagnostic criteria. Methods: Fifty-two unselected lung and bronchial biopsies were diagnosed by a thoracic pathologist based on a broad spectrum of immunohistochemical (IHC) stainings, molecular data and clini

Clinical validity of increased cortical uptake of [18F]flortaucipir on PET as a biomarker for Alzheimer’s disease in the context of a structured 5-phase biomarker development framework

Purpose: In 2017, the Geneva Alzheimer’s disease (AD) Biomarker Roadmap initiative adapted the framework of the systematic validation of oncological diagnostic biomarkers to AD biomarkers, with the aim to accelerate their development and implementation in clinical practice. With this work, we assess the maturity of [18F]flortaucipir PET and define its research priorities. Methods: The level of mat

Sociology of Knowledge and Production of Normative Power in the European Union’s External Actions

The article focuses on the entanglement between the EU’s attempts to construct its external actions in global politics and research on the EU as a global actor. The article argues that both the development of EU external actions and the sociology of knowledge production surrounding the analysis of these actions suffer from unnecessary dichotomisation. Advocates and analysts of the EU’s normative p

The Political Psychology of European Integration : being mindful of Europe

In an era of European crises over political legitimacy, economic austerity, and collapse of confidence in the EU the topic of European integration has be-come a very emotional subject. The anger which protestors demonstrate against economic austerity, the hate which nationalist far-right parties express for the EU and fellow Europeans, and the passion with which supporters of the EU argue for grea

Effects of forest fire smoke and volcanism on the stratospheric aerosol

Denna avhandling utforskar den stratosfäriska aerosolen genom både in-situ mätningar och fjärranalys. Bakgrundsaerosolen är komplex och påverkas av injektioner av skogsbrandrökspartiklar och av partiklar skapade från vulkaniskt SO2. Klimatmodeller behöver träffsäkra beskrivningar av den stratosfäriska aerosolen för att ha rimliga strålningsbudgetar. Genom att använda fjärranalystekniken satellitbuThis thesis explores the stratospheric aerosol through both in-situ measurements and remote sensing. The background stratospheric aerosol is complex and is perturbed by injections of forest fire smoke particles and by particles formed from volcanic SO2. Climate models need accurate description of the stratospheric aerosol in order to have sound radiation budgets. Using the remote sensing technique

Intraoperative ventilator settings and their association with postoperative pulmonary complications in neurosurgical patients : Post-hoc analysis of LAS VEGAS study

Background: Limited information is available regarding intraoperative ventilator settings and the incidence of postoperative pulmonary complications (PPCs) in patients undergoing neurosurgical procedures. The aim of this post-hoc analysis of the 'Multicentre Local ASsessment of VEntilatory management during General Anaesthesia for Surgery' (LAS VEGAS) study was to examine the ventilator settings o

Pain and functional outcomes in adult survivors of childhood cancer : A report from the St. Jude Lifetime Cohort study

Background: Although survivors of childhood cancer are at risk of chronic pain, the impact of pain on daily functioning is not well understood. Methods: A total of 2836 survivors (mean age, 32.2 years [SD, 8.5 years]; mean time since diagnosis, 23.7 years [SD, 8.2 years]) and 343 noncancer community controls (mean age, 35.5 years [SD, 10.2 years]) underwent comprehensive medical, neurocognitive, a

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I denne artikel sætter Rikke Lie Halberg både fokus på nationalmuseet som fænomen og rigsfællesskabets tre nationale museer. Museer, der formidler dele af en fælles fortid i rigsfællesskabet.

Association between hearing status and tinnitus distress

BackgroundDegree of distress perceived due to tinnitus is different in every individual. Underlying mechanisms for this are yet unclear.ObjectiveInvestigating the relationship between hearing status and tinnitus distress.Material and methodsThis is a case-control study. 38 individuals with tinnitus, divided into normal hearing (NHT, n = 19) and hearing impaired (HIT, n = 19) groups. Groups were ag

Increasing climatic sensitivity of global grassland vegetation biomass and species diversity correlates with water availability

Grasslands are key repositories of biodiversity and carbon storage and are heavily impacted by effects of global warming and changes in precipitation regimes. Patterns of grassland dynamics associated with variability in future climate conditions across spatiotemporal scales are yet to be adequately quantified. Here, we performed a global meta-analysis of year and growing season sensitivities of v

Use of measuring tools in practice development projects—A critical perspective

Background: Occupational therapists are generally positive towards use of measuring tools. However, such use may be problematic.Purpose: To illuminate hidden and adverse effects of using measuring tools in occupational therapy.Method: A Foucauldian inspired thematic analysis of the use of measuring tools in 13 reports of practice development projects in Denmark.Findings: Three themes were construcBackground.Occupational therapists are generally positive towards use of measuring tools. However, such use may be problematic.Purpose.To illuminate hidden and adverse effects of using measuring tools in occupational therapy.Method.A Foucauldian inspired thematic analysis of the use of measuring tools in 13 reports of practice development projects in Denmark.Findings.Three themes were constructed:

Impacts of long-term land use on terrestrial organic matter input to lakes based on lignin phenols in sediment records from a Swedish forest lake

Organic carbon burial in lake sediments plays an important role in the global carbon cycle, and is heavily affected by the terrestrial organic matter input. However, few studies have focused on long-term changes in terrestrial organic matter input to lakes in response to land-use changes. The aim of this study was to assess variations in sedimentary terrestrial organic matter over the last 1000 ye