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Spatial transcriptomics (ST) maps RNA level patterns within a tissue. This technology has not been previously applied to human placental tissue. We demonstrate analysis of human placental samples with ST. Unsupervised clustering revealed that distinct RNA patterns were found corresponding to different morphological structures. Additionally, when focusing upon terminal villi and hemoglobin associat

Symmetry-breaking charge separation in molecular materials has attracted increasing attention for optoelectronics based on single-material active layers. To this end, Fe(III) complexes with particularly electron-donating N-heterocyclic carbene ligands offer interesting properties with a 2LMCT excited state capable of oxidizing or reducing the complex in its ground state. In this Communication, we

In her own time, Anne Brontë the writer was regarded as inferior to the two older “Bells”, largely because of the perceived slightness of her first novel and the alleged coarseness and brutality of her second. For the next hundred years, it was accepted that she was a pale second-rater in relation to her sisters. That image has now been discarded; but the notion that Anne Brontë was not quite her

Soil is an interface of the lithosphere, biosphere, hydrosphere and atmosphere that provides a habitat for microbial growth. The microbial biomass forms an integral part of the soil. The physiological potential and diversity of the microbial communities in soils are strongly associated with the physicochemical properties of soils. The biotic and abiotic characteristics determine the structure and

Markis Claes Lagergren är en av den nyare svenska katolska kyrkohistoriens kanske märkligaste konvertiter. Han har i memoarverket "Mitt livs minnen" från 1920-talet skildrat sin konversion och sitt liv fram till 35-årsåldern, alltså perioden 1853 till 1887. Memoarerna bygger på hans dagboksanteckningar, vilka för den följande perioden utgivits i urval och som i original finns i hans samling på Nor

Invasive alien species are frequently discussed in academic literature by practitioners, government agencies, and popular media, but what does it mean for a species to be alien and why it this seen as a bad thing? To answer these questions, I have analysed texts about invasive alien species in academic journals and in communication from government agencies. The almost totally unanimous answer to t

PTSD symptomatology is known to be associated with executive dysfunction. Inhibitory control is a core component of executive functioning, and inhibitory skills are essential both for adequate functioning in everyday life and important in situations following trauma. The aim of the present study was to examine the relationship between trauma exposure, inhibitory control and PTSD symptomatology in

Background: Functionally related genes are well known to be often grouped in close vicinity in the genomes, particularly in prokaryotes. Notwithstanding the diverse evolutionary mechanisms leading to this phenomenon, it can be used to predict functions of uncharacterized genes. Methods: Here, we provide a simple but robust statistical approach that leverages the vast amounts of genomic data availa

Motivation: AliGater is an open-source framework to accelerate the development of bioinformatic pipelines for the analysis of large-scale, high-dimensional flow cytometry data. AliGater provides a Python package for automatic feature extraction workflows, as well as building blocks to construct analysis pipelines. Results: We illustrate the use of AliGater in a high-resolution flow cytometry-based

This chapter is a commentary on the book as a whole. Based on the overall PeTS project, the empirical findings from the four educational settings and the conceptual portions of the book, this chapter focuses on three specific aspects of peer group mentoring: the move from teaching as a private matter to teaching as a collegial responsibility, the relationship between collegiality and peer group me

This research concerns the influence of electric lighting on user behaviour in public squares and whether differences in people’s use of the square can be observed between daylight and darkness. Previous research on pedestrians suggests that lighting can support human needs for reassurance, accessibility, comfort and pleasure. While these findings are also likely to be applicable to the use of pub

Urothelial cancer of the urinary bladder frequently metastasizes to lymph-nodes, lungs, liver and bone. A taxonomy for molecular classification exists, but it is unknown if molecular subtypes show tropism for different organs. Here, we study 146 patients with de novo metastatic disease or recurrence after curative treatment. We classify primary tumors using two transcriptomic methods and immunosta

För tio år sedan, i oktober 2008 ockuperades en villa på Kävlingevägen. Huset ägdes av Lunds kommun och hade tidigare använts av socialförvaltningen, men hösten 2008 stod den tom sedan några år. Ockupanterna, ett tjugotal unga vuxna, döpte huset till Smultronstället med planer på att göra om det till både boende och självstyrande aktivitetshus. Ockupationen varade i tre veckor, och var del av en r

Frankrike har skakats av oroligheter sedan en 17-årig pojke sköts i samband med en trafikkontroll.Andrés Brink Pinto vill sätta upploppen i ett historiskt sammanhang.

Myocardial infarction (MI) leads to irreversible ischemic damage of the heart muscle and is the leading cause of heart failure. The ischemic cardiac injury triggers a potent local and systemic immune response. In the acute phase post-MI, neutrophils infiltrate the myocardium in large numbers and induce further cardiomyocyte death, expanding the infarcted area. The alarmin S100A8/A9 is a proinflamm

Characterization of the mechanical response of polymers and composite materials relies heavily on the macroscopic stress-strain response in uniaxial tensile configurations. To provide representative information, the deformation process must be homogeneous within the gauge length, which is a condition that is rarely achieved due to stress concentration or inhomogeneities within the specimen. In thi