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Popular Abstract in Swedish Bröstcancer är den vanligaste cancerformen i världen bland kvinnor och bara i Sverige insjuknar varje år runt 7000 personer. Vi vet att omkring 10-15% av fallen troligen beror på ärftliga faktorer och det har under senare tid gjorts stora insatser för att klargöra exakt vilka arvsanlag som har betydelse för utveckling av sjukdomen. Under början av 90-talet identifieradeHereditary breast cancer constitutes a considerable fraction of the total number of breast cancer cases occurring each year. Up until recently very few breast cancer predisposing genes were known, but many new common polymorphisms contributing to increased cancer susceptibility are continuously being identified. This thesis has focused on familial breast cancer and identifying as well as investi

Complex health systems make it difficult for older persons (75+) with multi-morbidity to achieve continuity of care. Case management could be one way to address this difficulty. Currently, there is a need to extend the knowledge regarding case management as experienced by those utilising the services, namely older persons (75+) with multi-morbidity. The study aimed to explore older persons' (75+)

Purpose – This paper aims to discuss a new tool for requirements gathering in the Web 2.0 era. It seeks to investigate the features that this kind of tool should have in order to be as widely applicable and useful as possible. Further, it aims to explore the extent to which business requirements for enterprise resource planning (ERP) systems can be collected and discussed collaboratively in a worl

The use of injection and brining as the first step in heavy salting of cod increases weight yields of the products through both salting and rehydration, compared to other pre-salting methods, like brining only and pickling. This is interesting since salt content of the muscle exceeds 20% NaCl, in all procedures. Therefore, the dissimilarities in yield were presumed to depend on the degree of prote

Over the years, much information has been gathered about fires in fire investigation reports and statistics. This information may have been collected nationally by an agency or an insurance company, or locally by the local rescue service. The information thus gathered can be used to learn from these fires and thereby lead to improved fire safety in buildings. This paper describes a method for discover

Abstract in UndeterminedThere has been much interest in group judgment and the so-called 'wisdom of crowds'. In many real world contexts, members of groups not only share a dependence on external sources of information, but they also communicate with one another, thus introducing correlations among their responses that can diminish collective accuracy. This has long been known, but it has-to date-

Elin Åkelius berättar om sitt examensarbete att återinventera sex rödlistade lavarter på bok. Det har visat sig att flera arter har gått tillbaka även under de senaste 20 åren.

We recently reported that HIV-1 infection can be inhibited by innate antimicrobial components of human seminal plasma (SP). Conversely, naturally occurring peptidic fragments from the SP-derived prostatic acid phosphatase ( PAP) have been reported to form amyloid fibrils called "SEVI'' and enhance HIV-1 infection in vitro. In order to understand the biological consequence of this proviral effect,

The consequences of adopting other definitions of the concepts of sum and convergence of a series are discussed in the light of historical and epistemological contexts. We show that some divergent series appearing in the context of renormalization methods cannot be assigned finite values while preserving a minimum of consistency with standard summation, without at the same time obtaining contradic

Objective To develop evidence-based recommendations for the diagnosis of knee osteoarthritis (OA). Methods The multidisciplinary guideline development group, representing 12 European countries, generated 10 key propositions regarding diagnosis using a Delphi consensus approach. For each recommendation, research evidence was searched systematically. Whenever possible, the sensitivity, specificity a

Transient evoked otoacoustic emissions (TEOAEs) have been analyzed for objective assessment of hearing function and monitoring of the influence of noise exposure and ototoxic drugs. This paper presents a novel application of the Hilbert-Huang transform (HHT) for detection and time-frequency mapping of TEOAEs. Since the HHT does not distinguish between signal and noise, it is combined with ensemble

Background: Potato late blight caused by the oomycete pathogen Phytophthora infestans can lead to immense yield loss. We investigated the transcriptome of Solanum tubersoum (cv. Desiree) and characterized the secretome by quantitative proteomics after foliar application of the protective agent phosphite. We also studied the distribution of phosphite in planta after application and tested transgeni

Background: Phosphoinositide 3-kinases (PI3Ks) are involved in a number of biologic responses. Recent preclinical studies demonstrated that the PI3K-dominant signal pathway could play an important role in the development of acute lung injury, although the mechanism remains unclear. Methods: CD-1 mice were administered different PI3K inhibitors either intranasally or intragastrically once a day for

What happens when cultural analysis enters the world of applied research and academics become consultants working with corporations and public institutions? The divide between academic research and commercial ethnography has often hampered communication and critical exchanges between these two worlds. In this paper we look at the experiences of consultants, drawing on Danish and Swedish examples.

Sammandrag. Uppsatsen är en studie av syntaktiska, semantiska och pragmatiska egenskaper hos konstruktionen x-som-x. Undersökningen tar sin utgångspunkt i den interaktionella grammatiken, och som jämförelsematerial används tidigare undersökningar av konstruktionen x-och-x. Exempel på x-som-x är hämtade från olika källor på Internet, såsom bloggar och diskussionsforum. I avsnittet om konstruktionen

Background: Mononuclear platinum anticancer agents hold a pivotal place in the treatment of many forms of cancers, however, there is a potential to improve response to evade resistance development and toxic side effects. BBR3464 is a promising trinuclear platinum anticancer agent, which is a polyamine mimic. The aim was to investigate the influence of polyamine pool reduction on the cytotoxic effe

We present a method aimed at reducing uncertainties and instabilities when characterizing materials in waveguide setups. The S-parameters for a rectangular waveguide loaded with a rectangular sample block are measured for three different sample orientations, and the corresponding geometries are modeled in a finite element program, taking any material parameters as input. The material parameters of