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Epileptogenesis is a complex process involving a multitude of changes at the molecular, cellular and network level. Previous studies have identified several key alterations contributing to epileptogenesis and the development of hyper-excitability in different animal models, but only a few have focused on the early stages of this process. For post status epilepticus (SE) temporal lobe epilepsy in p
In recent years, the term circular economy has become central in both research and politics. Inmost writings and policy documents, a circular economy is assumed to presuppose a break fromprevious habits and practices. Cultural and historical perspectives are often neglected, eventhough most preindustrial agriculture and food systems developed methods for the circulationand recycling of resources.
I naturen fångas solljus in via ljus-absorberande molekyler. På liknande sätt kan färgämnen användas för solcells- och artificiell fotosyntes-applikationer för att absorbera solljus, och överföra den exciterade elektronen.Framgångsrika färgämnen har tidigare varit baserade på Ru-polipyridyl-komplex, trots att Ru är ett av de mest ovanliga ämnena i jordskorpan. Detta arbete har som mål att ersätta Nature captures sunlight via light-absorbing molecules.Similarly, photosensitisers are used in applications of solar cells and artificial photosynthesis to absorb sunlight, and transfer the excited electron.Successful photosensitisers have in the past been based on a Ru polipyridyl scaffold, despite Ru being one of the scarcest elements in Earth's crust.This thesis work aims to replace Ru polipyri
In this article I investigate the spatial development of Swedish district courthouses and their different room types from 1970 to 2020, with attention to the specificities and commonalities with other building types. How have spatial form and use travelled between building types during this period, and how has this contributed to the recent, quite radical developments and transformation of the cou
A conceptual design of a year 2035 turbofan is developed and integrated onto a year 2035 aircraft model. The mission performance is evaluated for CO2, noise and NOx and is compared with a notional XWB/A350-model. An OGV heat exchanger is then studied rejecting heat from an electric generator, and its top-level performance is evaluated. The fan, the booster and the low-pressure turbine of the propu
Western missionaries became important eyewitnesses of the 1915 Armenian genocide, and many reported on the events. This article analyses witness reporting from a biographical and gendered perspective, taking into account the significance of studying local activism and transnational networks in a humanitarian setting. Taking the witness accounts of the Swedish missionary Alma Johansson as an exampl
Propolis is a resin-like material produced by bees from the buds of poplar and cone-bearing trees and is used in beehive construction. Propolis is a common additive in various biocosmetics and health-related products, despite the fact that it is a well-known cause of contact allergy. Caffeic acid and its esters have been the primary suspects behind the sensitization potency of propolis-induced con
A combustion Large Eddy Simulation (LES) is used to examine the flow, mixing, fuel-injection and combustion dynamics of a ramjet combustor with a cavity flame holder. The combustor is a running 50/50, in mole, ethylene/hydrogen fuel mixture. A direct-connect facility dual-mode ramjet/scramjet combustor presents the target case, with in the literature available experimental data is used in the pres
The semiconductor technology development con- stantly enables integrated circuits (ICs) with more, faster and smaller transistors. While there are many advantages, there are also many and new challenges, for example tighter margins, wear- outs and process variations. To address these challenges, the traditional approach with external test instruments used at man- ufacturing test must be complement
Aims: Pleural mesothelioma (PM) is a highly aggressive thoracic tumour with poor prognosis. Although reduced tissue drug accumulation is one of the key features of platinum (Pt) resistance, little is known about Pt distribution in human PM. Methods: We assessed Pt levels of blood samples and surgically resected specimens from 25 PM patients who had received neoadjuvant Pt-based chemotherapy (CHT).
Operando X-ray studies of chemical reactions have gained increasing interest lately, fueled by the emergence of a new generation of powerful focused X-ray sources. Although it is well known that ionizing radiation causes damage to samples via radical chemistry, this effect is often overlooked in studies of working devices or catalysts where intense focused beams are used as nanoscale probes. Here,
The work focuses on analysis and development of integrated low-pressure shaft generator in a geared twin-spool turbofan engine. It starts with manufacturing and evaluation of direct cooled hollow conductor coils, and has focus manufacturing, assembling and integration issues essential to machine design. The experiment-in-loop, but the model-based evaluation focuses not only on the coolant and cool
