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Chemical Abundances of Main-sequence, Turnoff, Subgiant, and Red Giant Stars from APOGEE Spectra. I. Signatures of Diffusion in the Open Cluster M67

Detailed chemical abundance distributions for 14 elements are derived for eight high-probability stellar members of the solar metallicity old open cluster M67 with an age of ∼4 Gyr. The eight stars consist of four pairs, with each pair occupying a distinct phase of stellar evolution: two G dwarfs, two turnoff stars, two G subgiants, and two red clump (RC) K giants. The abundance analysis uses near

Reducing health inequalities with interventions targeting behavioral factors among individuals with low levels of education - A rapid review

Individuals with low levels of education systematically have worse health than those with medium or high levels of education. Yet there are few examples of attempts to summarize the evidence supporting the efficacy of interventions targeting health-related behavior among individuals with low education levels, and a large part of the literature is descriptive rather than analytical. A rapid review

Center of excellence funding : Connecting organizational capacities and epistemic effects

This study investigates the relationship between resource concentration/stability and new results/breakthroughs in the context of a Swedish Center of Excellence (CoE) scheme. A common assumption in using the CoE instrument is that there is a scale return to research on concentration of funds. However, the details of how funding connects to such returns are typically assumed rather than empirically

Fluorine in the solar neighborhood : Chemical evolution models

Context. In light of new observational data related to fluorine abundances in solar neighborhood stars, we present chemical evolution models testing various fluorine nucleosynthesis prescriptions with the aim to best fit those new data. Aim. We consider chemical evolution models in the solar neighborhood testing various nucleosynthesis prescriptions for fluorine production with the aim of reproduc

Utility of Resazurin, Horseradish Peroxidase, and NMR Assays to Identify Redox-Related False-Positive Behavior in High-Throughput Screens

Discerning false positives from true actives in high-throughput screening (HTS) output is fraught with difficulty as the reason of anomalous activity seen for compounds is often not clear-cut. In this study, we introduce a novel medium-throughput NMR assay for the identification of redox-cycling compounds (RCCs), which is based on detection of oxidation of a reducing agent. We compare its outcomes

Extracellular retention of PDGF-B directs vascular remodeling in mouse hypoxia-induced pulmonary hypertension

Pulmonary hypertension (PH) is a lethal condition, and current vasodilator therapy has limited effect. Antiproliferative strategies targeting platelet-derived growth factor (PDGF) receptors, such as imatinib, have generated promising results in animal studies. Imatinib is, however, a nonspecific tyrosine kinase inhibitor and has in clinical studies caused unacceptable adverse events. Further studi

The β-Ketoacyl-CoA Synthase Hv KCS1, Encoded by Cer-zh, Plays a Key Role in Synthesis of Barley Leaf Wax and Germination of Barley Powdery Mildew

The cuticle coats the primary aerial surfaces of land plants. It consists of cutin and waxes, which provide protection against desiccation, pathogens and herbivores. Acyl cuticular waxes are synthesized via elongase complexes that extend fatty acyl precursors up to 38 carbons for downstream modification pathways. The leaves of 21 barley eceriferum (cer) mutants appear to have less or no epicuticul

Determining the Accuracy and Reliability of Indirect Calorimeters Utilizing the Methanol Combustion Technique

Background: Several indirect calorimetry (IC) instruments are commercially available, but comparative validity and reliability data are lacking. Existing data are limited by inconsistencies in protocols, subject characteristics, or single-instrument validation comparisons. The aim of this study was to compare accuracy and reliability of metabolic carts using methanol combustion as the cross-labora

Tuning the morphology of self-assisted GaP nanowires

Patterned arrays of self-assisted GaP nanowires (NWs) were grown on a Si substrate by gas source molecular beam epitaxy using various V/III flux ratios from 1-6, and various pitches from 360-1000 nm. As the V/III flux ratio was increased from 1-6, the NWs showed a change in morphology from outward tapering to straight, and eventually to inward tapering. The morphologies of the self-assisted GaP NW

Armed forces in disaster response : Problems and perspectives on disaster governance in India

Abstract: This chapter looks at the challenges of disaster governance in India. It highlights the problems of engaging the Armed Forces as the responder to disasters given the prevalent sociological dynamics within the communities. The Armed Forces in India have successfully responded to several catastrophes such as the Gujarat earthquake, the Indian Ocean tsunami, the Kashmir earthquake and the m

Double Compression Expansion Engine Concepts : Efficiency Analysis over a Load Range

Double Compression Expansion Engine (DCEE) concepts are split-cycle concepts where the main target is to improve brake efficiency. Previous simulations work [1] suggests these concepts has a potential to significantly improve brake efficiency relative to contemporary engines. However, a high peak efficiency alone might be of limited value. This is because a vehicle must be able to operate in diffe

Feedback in Small Systems -A Stochastic Thermodynamic Perspective

Recent advances in nanotechnology and the accompanying development oftechniques that operate and manipulate systems on the micro- and nanometer scale have driven the development of stochastic thermodynamics. This isa theory that can describe small systems far from equilibrium, where the fluctuations are of the same order of magnitude as the mean values. Stochasticthermodynamics can be used to prov

The theology of the land in Jewish-Christian relations and its role in misunderstandings between jews and Christians

Without sufficient knowledge of the painful history of Jewish-Christian apologetics and polemics, which have their origins in late antiquity and continued on into the medieval period, it is easy to fail to recognise the complexities of current Christian approaches to the Land that is now known as Israel and/or Palestine. Jesper Svartvik here examines the interplay of theology and politics, and, in

Cylinder Pressure Based Virtual Sensor for In-Cycle Pilot Mass Estimation

In this paper, a virtual sensor for the estimation of the injected pilot mass in-cycle is proposed. The method provides an early estimation of the pilot mass before its combustion is finished. Furthermore, the virtual sensor can also estimate pilot masses when its combustion is incomplete. The pilot mass estimation is conducted by comparing the calculated heat release from in-cylinder pressure mea

The Potential of SNCR Based NOx Reduction in a Double Compression Expansion Engine

Selective Non-Catalytic Reduction (SNCR), used to reduce the emissions of nitrogen oxides (NOx), has been a well-established technology in the power plant industry for several decades. The SNCR technique is an aftertreatment strategy based on thermal reduction of NOx at high temperatures. In the compression ignition engine application, the technology has not been applicable due to low exhaust temp

Inter-phase charge and energy transfer in Ruddlesden-Popper 2D perovskites : Critical role of the spacing cations

Photo-generated charge carrier dynamics in Ruddlesden-Popper 2D perovskites with linear (n-BA) and branched (iso-BA) butylamine as spacing cations have been studied by using transient absorption and time-resolved photoluminescence spectroscopies. Both n-BA and iso-BA perovskites consist of mixed-phase 2D quantum wells with various layer thicknesses, where the photo-generated charges undergo inter-

Between Values and the World : Studies in second-order value theory

Value is an inescapable part of the human experience and what life must be like for a conscious and feeling person. Philosophical questions about value are therefore naturally invited: What sort of thing would value be if it were part of the furniture of the world? How should we understand the relations that value is thought to stand in to other things? In a broad sense, these are formal questions

A Swedish national adoption study of risk of irritable bowel syndrome (IBS)

Objectives: Irritable bowel syndrome (IBS) clusters in families, but the familial risk of IBS has not been determined in adoptees. Studying adoptees and their biological and adoptive parents is a strong study design for separating genetic from environmental causes of familial clustering. This nationwide study aimed to separate the biological (genetic) and familial environmental contribution to the