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The lower Cambrian Lagerstätte of Sirius Passet, Peary Land, North Greenland, is one of the oldest of the Phanerozoic exceptionally preserved biotas. The Lagerstätte evidences the escalation of numbers of new body plans and life modes that formed the basis for a modern, functionally tiered ecosystem. The fauna is dominated by predators, infaunal, benthic and pelagic, and the presence of abundant n
Vilda djur påverkas ständigt av omgivningens temperatur som, tillsammans med ytterligare faktorer, styr många av de mönster och beteenden vi ser hos djur i naturen. Förändringar i temperatur kan till exempel påverka hur populationer och individer rör sig över tid och rum, när de väljer att fortplanta sig samt hur mycket föda som finns att tillgå. För jämnvarma djur, fåglar och däggdjur, som producAnimals constantly need to relate to prevailing environmental conditions and regulate their body temperature accordingly. Body temperature regulation in birds and mammals is inherently linked to energy expenditure and, thus, thermoregulation is a physiological mechanism that could trade-off with other costly processes, with potential long-term fitness consequences. In this thesis, I studied ecolog
The flame dynamics in a novel, ultra-lean non-premixed model gas turbine (GT) burner flame was numerically studied using large eddy simulation (LES) coupled with probability density function (PDF) based on the Euler stochastic field (ESF) method. One non-reacting case and three reacting cases with global equivalence ratio ϕglob=1.0,0.6,0.3 were simulated. Comparison of mean flow fields and OH dist
Microbial responses to Cu pollution as a function of Cu sources (Cu salts and commercial Cu fungicides) were assessed in a soil using basal soil respiration, and bacterial and fungal community growth, as endpoints. The soil was amended with different concentrations (0–32 mmol Cu kg−1) of Cu nitrate, Cu sulfate, Bordeaux mixture and 3 types of Cu oxychloride. Cu salts decreased soil pH, while this
Introduction: MR-safety remains a concern among MR professionals. We aimed to evaluate the extent of MR-related incidents using a national database and a questionnaire among MR professionals and to identify possible predictors for MR-related incidents. Methods: MR-related incidents reported to a national database from 2015 to 2017 were scrutinized. A national online survey focussing on MR safety a
Currently, many research studies are exploring opportunities for the use of novel fuels and of their blends with conventional, i.e. petroleum-based fuels. To pave the way for their acceptance and implementation in the existing energy market, a comprehensive knowledge about their combustion properties is inevitable, among others. Within this context, alcohols, with butanol in particular, are consid
This article presents the methodological requirements for clinical examination and patient-reported outcomes measurements. The assessment of any measurement for clinical research in hand surgery is difficult. A method of measuring a criterion could be 100% reliable but 100% invalid. Bias may be present in our assessment if we do not take into account the methodological requirements related to reli
Historically, treatment based on the availability of clotting factor replacement has resulted in an arcane guideline for the correction of factor deficiencies in people with haemophilia (PwH). While all other disease entities seek to restore function to a normal level, PwH are restricted to factor nadirs still equivalent to mild or moderate disease, resulting in continued risk of bleeding. A new t
Background: Prophylaxis with factor VIII (FVIII) should be individualized based on patient characteristics, including FVIII pharmacokinetics. Population pharmacokinetic (popPK) modeling simplifies pharmacokinetic studies by obviating the need for multiple samples. Objective: The objective of this study was to characterize the pharmacokinetics and inter-individual variability (IIV) of BAY 94-9027 i
Objectives: We aimed to identify and evaluate: (1) treatment-emergent adverse events (TEAE (worse or new since baseline)) and the subgroup of severe TEAEs in a placebo-controlled 7-day randomised trial of regular, low-dose, sustained-release oral morphine for chronic breathlessness and (2) clinical characteristics associated with TEAE. Methods: Safety analysis of trial data. Adults with chronic br
The process of protein crystallization from aqueous protein solutions is still insufficiently understood. During macroscopic crystal formation, occurring often on time scales from a few hours to several days, protein dynamics evolves on the molecular level. Here, we present a proof of concept and a framework to observe this evolving diffusive dynamics on the pico- to nanosecond time scale, associa
Aim: To evaluate person-centeredness in nursing homes from the perspective of frail older persons, before and after implementing an educational intervention about palliative care. Design: A crossover design. Methods: Forty-four older persons living in nursing homes were interviewed. A convergent mixed-method was used to analyse data. Results: The older persons expressed feelings of unsafety relate
Conflicts of interests between males and females over reproduction is a universal feature of sexually reproducing organisms and has driven the evolution of intersexual mimicry, mating behaviours and reproductive polymorphisms. Here, we show how temperature drives pre-reproductive selection in a female colour polymorphic insect that is subject to strong sexual conflict. These species have three fem
This paper presents the architecture and the corresponding simulation results for a very low power half-rate extended Hamming (8,4) decoder implemented in analog integrated circuitry. TI’s 65nm low power CMOS design library was used to simulate the complete decoder including an input interface, an analog decoding core and an output interface. The simulated bit error rate (BER) performance of the d
Iron N-heterocyclic carbene (NHC) complexes have received a great deal of attention recently because of their growing potential as light sensitizers or photocatalysts. We present a sub-ps X-ray spectroscopy study of an FeIINHC complex that identifies and quantifies the states involved in the deactivation cascade after light absorption. Excited molecules relax back to the ground state along two pat
Using 10 polymorphic microsatellites and 1251 individual samples (some dating back to the early 1980s), genetic structure and effective population size in all native and introduced Swedish populations of the European wels catfish or Silurus glanis were studied. Levels of genetic variability and phylogeographic relationships were compared with data from a previous study of populations in other part
Background and purpose — Having patients self-evaluate the outcome is an important part of the follow-up after knee arthroplasty. The Forgotten Joint Score-12 (FJS-12) introduced joint awareness as a new approach, suggested to be sensitive enough to differentiate well-functioning patients. This study evaluated the Swedish translation of the FJS-12 and investigated the validity, reliability, and in
The purpose of this report is to discuss how a decarbonising the steel, plastic, and paper industries may affect economic growth, wages and employment in the European Union (EU). We approach the issue from two different angles. First, we discuss how a decarbonization of the three industries may affect the rest of the economy. Second, we discuss how a decarbonization of the three industries may aff
