We introduce partially defined dynamical systems defined on a topological space. To each such system we associate a functor s from a category G to Topop and show that it defines what we call a skew category algebra A ⋊ G. We study the connection between topological freeness of s and, on the one hand, ideal properties of A ⋊ G and, on the other hand, maximal commutativity of A in A ⋊ G. In particul

Aims/hypothesis An abnormal urinary albumin excretion rate (AER) is often the first clinically detectable manifestation of diabetic nephropathy. Our aim was to estimate the heritability and to detect genetic variation associated with elevated AER in patients with type 1 diabetes. Methods The discovery phase genome-wide association study (GWAS) included 1,925 patients with type 1 diabetes and with

In-situ wide-angle X-ray scattering (WAXS) measurements have been conducted on atmosphericpressure fuel-rich premixed freely propagating ethylene/oxygen flames with argon and nitrogen dilution. In this work, a novel analysis methodology able to provide quantitative information on soot/carbon particle species and concentrations was tested under heavy sooting conditions. The particle composition and

This article takes its point of departure in the assumption that values shape planning practices and that alternatively one can reconstruct such values from the way planning interventions are argued and evaluated. We contend that planners' discourses involve implicit value commitments that are observable in their representations of public space and implicated in the results of public-space plannin

Changes in pollen and spore assemblages across the Cretaceous-Paleogene (K-Pg) boundary elucidate the vegetation response to a global environmental crisis triggered by an asteroid impact in Mexico 66 Ma. The Cretaceous-Paleogene boundary clay, associated with the Chicxulub asteroid impact event, constitutes a unique, global marker bed enabling comparison of the world-wide palynological signal span

The Z -> tau tau cross section is measured with the ATLAS experiment at the LHC in four different final states determined by the decay modes of the tau leptons: muon-hadron, electron-hadron, electron-muon, and muon-muon. The analysis is based on a data sample corresponding to an integrated luminosity of 36 pb(-1), at a proton-proton center-of-mass energy of root s = 7 TeV. Cross sections are measu

Green spaces are recognized for improving mental health, but what particular kind of nature is required is yet not elucidated. This study explores the effect of specific types of recreational nature qualities on mental health. Longitudinal data (1999/2000 and 2005) from a public health survey was distributed to a stratified sample (n = 24,945) of a Swedish population. People from rural or suburban

Power system voltage security assessment is generally applied by considering the power system loadability surface. For a large power system, the loadability surface is a complicated hyper-surface in parameter space, and local approximations are a necessity for any analysis. Unfortunately, inequality constraints due to for example generator overexitation limiters, and higher codimension bifurcation

Carotid intima-media thickness (CIMT) is a marker of cardiovascular risk. It is unclear whether measurement of mean common CIMT improves 10-year risk prediction of first-time myocardial infarction or stroke in individuals with elevated blood pressure. We performed an analysis among individuals with elevated blood pressure (ie, a systolic blood pressure 140 mm Hg and a diastolic blood pressure 90 m

After oesophageal cancer surgery quality of life (QOL) is severely reduced for a long time. Even though this is a well-documented fact no previous studies have focused on the patients' experiences of supportive care after surgery. PURPOSE: To illuminate patients' experiences of supportive care from a long-term perspective after oesophagectomy or oesophagogastrectomy for cancer. METHOD: Data collec

To investigate the hospital cost and short-term clinical outcome of traditional minimally invasive versus robot-assisted hysterectomy in women primarily considered unavailable for vaginal surgery.

This paper follows directly from an earlier paper where we discussed the requirements for an artifact to be a moral agent and concluded that the artifactual question is ultimately a red herring. As before, we take moral agency to be that condition in which an agent can appropriately be held responsible for her actions and their consequences. We set a number of stringent conditions on moral agency.

OBJECTIVES:: In a recent study hypnosis has been found to relieve persistent idiopathic orofacial pain. Quantitative sensory testing (QST) is widely used to evaluate somatosensory sensitivity, which has been suggested as a possible predictor of management outcome. The objectives of this study were to examine: (1) possible associations between clinical pain relief and baseline somatosensory sensiti

We report an element-specific investigation of electronic and magnetic properties of the graphene/Ni(111) system. Using x-ray magnetic circular dichroism, the occurrence of an induced magnetism of the carbon atoms in the graphene layer is observed. We attribute this magnetic moment to the strong hybridization between C pi and Ni 3d valence band states. The net magnetic moment of carbon in the grap

Novel adjuvants and antigen-delivery systems with immunomodulatory properties that shift the allergenic Th2 response towards a Th1 or regulatory T cell response are desired for allergen-specific immunotherapy. This study demonstrates that 200-nm sized biodegradable poly(gamma-glutamic acid) (gamma-PGA) nanoparticles (NPs) are activators of human monocyte-derived dendritic cells (MoDCs). gamma-PGA

Diamond-Blackfan anemia is a congenital erythroid hypoplasia caused by functional haploinsufficiency of genes encoding ribosomal proteins. Mutations involving the ribosomal protein S19 gene are detected in 25 % of patients. Enforced expression of ribosomal protein S19 improves the overall proliferative capacity, erythroid colony-forming potential and erythroid differentiation of hematopoietic prog

Irish peat soils are extensive, covering approximately 14-20% of the national land area. They contain between 53% and 62% of the national soil organic carbon stock. Montane blanket bog covers approximately 25% or 242650ha of the total peatland area in Ireland and is the dominant peatland type covering the upland area of Wicklow. Blanket bogs are very sensitive systems and have experienced much dis

Insomnia and short and long sleep durations have all been linked to cardiovascular disease. Male gender and low socioeconomic status are also related to cardiovascular disease, but it is unclear whether these two factors modify the impact of poor sleep on cardiovascular disease incidence.