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Functioning Numbness Instead of Feelings as a Direction : Young Adults’ Experiences of Antidepressant Use
In this article we explore, through in-depth interviews, young adults’ experiences of depression and antidepressant use in contemporary neoliberal society. We show that medication initially brings relief and an ability to function. However, in the longer perspective the dominating experience of antidepressants is emotional numbness. We suggest that this functioning yet numb subject is well suited
Loss of Dystrophin and β-Sarcoglycan, Respectively, Significantly Exacerbates the Phenotype of Laminin α2 Chain-Deficient Animals.
The adhesion molecule laminin α2 chain interacts with the dystrophin-glycoprotein complex, contributes to normal muscle function, and protects skeletal muscles from damage. Complete loss of the laminin α2 chain in mice results in a severe muscular dystrophy phenotype and death at approximately 3 weeks of age. However, it is not clear if the remaining members of the dystrophin-glycoprotein complex
Amaryllidaceae och Iridaceae i Norden, del 2.
Abstract is not available
Emergence of New ALK Mutations at Relapse of Neuroblastoma.
In neuroblastoma, the ALK receptor tyrosine kinase is activated by point mutations. We investigated the potential role of ALK mutations in neuroblastoma clonal evolution.
Inhibition of Polyamine Formation Antagonizes Vascular Smooth Muscle Cell Proliferation and Preserves the Contractile Phenotype.
The polyamines putrescine, spermidine and spermine play essential roles in cell proliferation and migration, two processes involved in the development of vascular disease. Thus, intervention with polyamine formation may represent a way to inhibit unwanted vascular smooth muscle cell (VSMC) proliferation. The aim of the present study was to assess the importance of polyamines for VSMC proliferation
Genetic variation in the moss Homalothecium lutescens in relation to habitat age and structure
Relationships between genetic (allozyme) variation and landscape age and structure were investigated in 17 calcareous grassland demes of the moss Homalothecium lutescens (Hedw.) H. Rob. on the Baltic island of Oland. Mean within-deme gene diversity (H-S = 0.152) was moderate compared with other bryophyte studies, and the between-deme proportion of the total diversity (G(ST) = 0.100, Jost's D = 0.0
Expression Quantitative Trait Loci Acting Across Multiple Tissues Are Enriched in Inherited Risk for Coronary Artery Disease.
-Despite recent discoveries of new genetic risk factors, the majority of risk for coronary artery disease (CAD) remains elusive. As the most proximal sensor of DNA variation, RNA abundance can help identify subpopulations of genetic variants active in and across tissues mediating CAD risk through gene expression.
Safeguards of a Disunified Mind
Vitamin D insufficiency over 5 years is associated with increased fracture risk-an observational cohort study of elderly women.
This study of elderly Swedish women investigated the association between chronic vitamin D insufficiency and osteoporotic fractures occurring between ages 80-90. The incidence and risk of hip and major osteoporotic fractures was significantly higher in elderly women with low vitamin D levels maintained over 5 years.
Fecundity selection does not vary along a large geographical cline of trait means in a passerine bird
Local environmental and ecological conditions are commonly expected to result in local adaptation, although there are few examples of variation in phenotypic selection across continent-wide spatial scales. We collected standardized data on selection with respect to the highly variable plumage coloration of pied flycatcher (Ficedula hypoleucaPall.) males from 17 populations across the species' bree
Elliptic and Hexadecapole Flow of Charged Hadrons in Au plus Au Collisions at root s(NN)=200 GeV
Differential measurements of the elliptic (upsilon(2)) and hexadecapole (upsilon(4)) Fourier flow coefficients are reported for charged hadrons as a function of transverse momentum (p(T)) and collision centrality or number of participant nucleons (N-part) for Au + Au collisions at root s(NN) = 200 GeV/ The upsilon(2,4) measurements at pseudorapidity vertical bar eta vertical bar
Fast Exciton Dynamics and Coherent Oscillations Revealed by Coherent 2D Spectroscopy in Chlorosomes
In this study ultrafast energy transfer dynamics in chlorosomes from sulphur bacterium Chlorobaculum tepidum were explored by means of coherent electronic two-dimensional spectroscopy. Observed sub-100 fs dynamics were attributed to incoherent downhill excitation diffusion between disordered domains within chlorosomes. At the same time vibrational coherent oscillations were investigated on the lon
Indices of methylation in sperm DNA from fertile men differ between distinct geographical regions.
Which are the main determinants, if any, of sperm DNA methylation levels?
Mixing thermodynamics of TM1-xGdxN (TM=Ti, Zr, Hf) from first principles
The mixing thermodynamics of GdN with TiN, ZrN, and HfN is studied using first-principles methods. We find that while Ti1-xGdxN has a strong preference for phase separation due to the large lattice mismatch, Zr1-xGdxN and Hf1-xGdxN readily mix, possibly in the form of ordered compounds. In particular, ZrGdN2 is predicted to order in a rocksalt counterpart to the L1(1) structure at temperatures bel
High-Throughput Hardware-Efficient Soft-Input Soft-Output MIMO Detector for Iterative Receivers
Operational Improvements for Startup Time Reduction in Solar Steam Turbines
Solar steam turbines are subject to high thermal stresses as a result of temperature gradients during transient operation, which occurs more frequently due to the variability of the solar resource. In order to increase the flexibility of the turbines while preserving lifting requirements, several operational modifications for maintaining turbine temperatures during offline periods are proposed and
A Model for Evaluating the Effects of Blunt Skeletal Muscle Trauma on Microvascular Permeability and Plasma Volume in the Rat
The objective of the present study was to develop an experimental model suitable for studying the effects of a nonhemorrhagic soft tissue trauma on plasma volume (PV) and microvascular permeability. Anesthetized Sprague-Dawley rats were exposed to a sham procedure or a laparotomy followed by a standardized trauma to the abdominal rectus muscle. We evaluated the effects of trauma on transcapillary
Acceptable noise level with Danish, Swedish, and non-semantic speech materials.
Objective: Acceptable noise level (ANL) has been established as a method to quantify the acceptance of background noise while listening to speech presented at the most comfortable level. The aim of the present study was to generate Danish, Swedish, and a non-semantic version of the ANL test and investigate normal-hearing Danish and Swedish subjects' performance on these tests. Design: ANL was meas
The Scholar as Squirrel : Everyday Collecting in Academia
This paper looks at collecting practices in the everyday world of universities. How do scholars turn into hoarding squirrels, creating their own archives? My focus is on routines and technologies, which deal with storage and order as well as retrieving and discarding of research materials.