Antiproliferative effects of curcuphenol, a sesquiterpene phenol.
Curcuphenol is a sesquiterpene isolated from sponges and plants having several significant biological activities. The present study explored its effect on cell proliferation and apoptosis in Caco-2 human colon cancer cells. It was demonstrated that curcuphenol in concentrations in the range of 29-116microg/ml inhibited cell proliferation and DNA replication and induced cell death in a dose-depende
