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Background and Purpose-Previous studies demonstrated association between mitochondrial DNA variants and ischemic stroke (IS). We investigated whether variants within a larger set of oxidative phosphorylation (OXPHOS) genes encoded by both autosomal and mitochondrial DNA were associated with risk of IS and, based on our results, extended our investigation to intracerebral hemorrhage (ICH). Methods-

Background: Vitamin A may have some influence on the immune system, but the role in allergy modulation is still unclear. Objective: To clarify whether high levels of retinoic acid (RA) affects allergic response in vivo, we used a murine experimental model of airway allergic disease. Methods: Ovalbumin (OVA)-immunization/OVA-challenge (OVA/OVA) and house dust mite (HDM)-immunization/HDM-challenge (

We investigate whether it is possible that viable microbes could have been transported to the Earth from planets in extra-solar systems by means of natural vehicles such as ejecta expelled by comets or asteroid impacts on such planets. The probabilities of close encounters with other solar systems are taken into account as well as the limitations of bacterial survival times inside ejecta in space,

The primary goal of this study was to examine whether changes in the temporal distance of a moral dilemma affect how it is perceived and subsequently resolved. Based on Construal Level Theory (Trope & Liberman, 2003), it was predicted that the relative weight of abstract justice features should increase and the relative weight of concrete care features should decrease with temporal distance. T

Evidence-based knowledge of how to guide the mothers of preterm infants in breastfeeding establishment is contradictive or sparse. The aim was to investigate the associations between pre-specified clinical practices for facilitating breastfeeding, and exclusive breastfeeding at discharge as well as adequate duration thereof.

Popular Abstract in Swedish Bröstcancer är den vanligaste cancerformen bland kvinnor i Sverige. Ungefär var tionde kvinna beräknas drabbas av bröstcancer, och i Sverige insjuknar ungefär 7.000 kvinnor årligen. Glädjande nog har överlevnaden förbättrats och nästan 90% lever 5 år efter sin diagnos och cirka två tredjedelar kan anses botade. Trots detta dör cirka 1.500 kvinnor i sjukdomen i Sverige vBreast tumours harbour a large amount of genetic and epigenetic alterations, which are associated with e.g. tumour aggressiveness, prognosis, and response to therapy. The heterogeneity of breast tumours is reflected in the identification of at least five molecular subtypes named basal-like, luminal A, luminal B, HER2-enriched and normal-like, which are believed to originate from different cell typ

Performance improvements are always needed in computer graphics. Better performance frees up computational resources which can be used to increase the level of realism in the rendered images. Despite a very rapid development of graphics hardware, we are still far from the point where photo-realistic rendering can be done in real time. Therefore, better algorithms must be developed in order to adva

Syftet med rapporten har varit att analysera erfarenheterna av miljöanpassad upphandling och innovationsupphandling, samt hur dessa styrmdel kan bidra till uppfyllandet av olika politiska målsättningar. Rapporten redogör bl.a. för målsättningarna för upphandling, betydelsen av en efterfrågedriven innovationspolitik, samt hur upphandling kan samverka med andra styrmedel på miljöområdet.

Objective To estimate the diagnostic accuracy and interobserver agreement in predicting intracavitary uterine pathology at offline analysis of three-dimensional (3D) ultrasound volumes of the uterus. Methods 3D volumes (unenhanced ultrasound and gel infusion sonography with and without power Doppler, i.e. four volumes per patient) of 75 women presenting with abnormal uterine bleeding at a bleeding

Aims: The aim of this study was to determine the incidence of neonatal morbidity in extremely preterm infants and to identify associated risk factors. Methods: Population based study of infants born before 27 gestational weeks and admitted for neonatal intensive care in Sweden during 2004-2007. Results: Of 638 admitted infants, 141 died. Among these, life support was withdrawn in 55 infants becaus

The ATLAS Collaboration measures the inclusive production of Z bosons via their decays into electron and muon pairs in p + Pb collisions at root S-NN = 5.02 TeV at the Large Hadron Collider. The measurements are made using data corresponding to integrated luminosities of 29.4 and 28.1 nb(-1) for Z -> ee and Z -> mu mu, respectively. The results from the two channels are consistent and combined to

Although COPD is a major disease worldwide there is a perplexing current uncertainty about the nature of this disease. COPI) is characterized at onset and prevalently by the involvement of the lungs and bronchi, but as the disease evolves abnormalities develop in other organs and systems and the question arises: what is the pathogenesis of these respiratory and systemic impairments? Are the altera

Artikel om den brittiska filmen Chariots of Fire från 1981, dess skildring av Paris-OS 1924, hur den avspeglar stämningar kring 1980 och hur den fick ny aktualitet i samband med London-OS 2012.

Chronic obstructive pulmonary disease (COPD) is characterised by a chronic inflammation in conducting airways and the alveolar parenchyma. The inflammation, which is a consequence of inhalation of noxious gases like tobacco smoke, has traditionally been thought to be driven by innate immune responses. However, more recent studies have revealed an increase in lymphocyte-rich lymphoid aggregates (LA

We demonstrate the use of a GaAs-AlGaAs gated tunnel diode (GTD) in an ultra-wideband (UWB) wavelet generator. An inductor is integrated to form an oscillator circuit, which is driven by the negative differential conductance property of a GTD. It is demonstrated that as the gate tunes the magnitude of the output conductance, the oscillator may be switched on and off, creating short RF pulses. The

Vascular complications of diabetes account for the majority of morbidity and mortality among diabetic patients. Large clinical trials have identified hyperglycemia as a risk factor in the development of diabetic vascular complications. The effects of hyperglycemia on the vessel wall are not fully understood, but chronic vascular inflammation has been implicated to play a major role in the pathogen