The possibility of imaging single proteins constitutes an exciting challenge for x-ray lasers. Despite encouraging results on large particles, imaging small particles has proven to be difficult for two reasons: not quite high enough pulse intensity from currently available x-ray lasers and, as we demonstrate here, contamination of the aerosolized molecules by nonvolatile contaminants in the soluti

We use extremely bright and ultrashort pulses from an x-ray free-electron laser (XFEL) to measure correlations in x rays scattered from individual bioparticles. This allows us to go beyond the traditional crystallography and single-particle imaging approaches for structure investigations. We employ angular correlations to recover the three-dimensional (3D) structure of nanoscale viruses from x-ray

Single-particle diffraction from X-ray Free Electron Lasers offers the potential for molecular structure determination without the need for crystallization. In an effort to further develop the technique, we present a dataset of coherent soft X-ray diffraction images of Coliphage PR772 virus, collected at the Atomic Molecular Optics (AMO) beamline with pnCCD detectors in the LAMP instrument at the

Single particle diffractive imaging data from Rice Dwarf Virus (RDV) were recorded using the Coherent X-ray Imaging (CXI) instrument at the Linac Coherent Light Source (LCLS). RDV was chosen as it is a well-characterized model system, useful for proof-of-principle experiments, system optimization and algorithm development. RDV, an icosahedral virus of about 70 nm in diameter, was aerosolized and i

Background: Respiratory symptoms are common in the general adult population. Increased burden of respiratory symptoms may increase the risk of mortality. We assessed the association between respiratory symptom clusters and mortality. Methods: Participants were derived from two population-based Swedish adult cohorts (N = 63,060). Cluster analysis was performed with Locality Sensitive Hashing (LSH)-

This paper proposes an alternative semi-analytical Fourier modal method adapted for general periodic anisotropic gratings made of dielectrics with moderate to low index profiles corresponding to materials ranging from conventional dielectric 3D printing materials to ceramic materials. The proposed method is closely related to classical Rigorous Coupled-Wave Analysis built on scattering matrices, h

Serial crystallography (SX) at both X-ray free-electron lasers (XFELs) and synchrotrons offers the possibility to collect data at non-cryogenic temperature almost radiation damage free and enables time-resolved crystallography of irreversible reactions. The necessary steady delivery of new micron-sized crystals of biological macromolecules sets it apart from traditional single crystal macromolecul

ObjectiveRecent studies suggest that immigrants trade youth when partnering with members of the White majority population. This study contributes to this emerging literature by examining whether this trade should be understood as differential treatment based on immigrant status or as a broader dynamic of racial preferences in the marriage market.MethodsThis study compares age gaps in unions of int

This study investigates the ignitability of hydrogen in an optical heavy-duty SI engine. While the ignition energy of hydrogen is exceptionally low, the high load and lean mixtures used in heavy-duty hydrogen engines lead to a high gas density, resulting in a much higher breakdown voltage than in light-duty SI engines. Spark plug wear is a concern, so there is a need to minimise the spark energy w

We propose a dynamical model depicting nitrogen (N2) fixation (diazotrophy) in a unicellular cyanobacterium, Crocosphaera watsonii, grown under light limitation and obligate diazotrophy. In this model, intracellular carbon and nitrogen are both divided into a structual pool and a storage pool. An internal pool that explicitly describes the nitrogenase enzyme is also added. The model is successfull

I en svår tid kan ett enkelt digitalt upplägg innebära både glädje och lättnad för många människor. Det skriver forskarna Tove Harnett, Sofi Fristedt och Håkan Jönson tillsammans med Eva Wiman, anhörigrådgivare och verksamhetsansvarig vid Malmö anhörigförening.

This volume highlights the intricate relationship between religion, migration, and policy-making. It does so by investigating matters in different corners of Europe, from Iceland in the north to Spain in the south. With a clear focus on minority religions on the one hand and how Christianity is used to construct a European identity on the other, the authors provide insights into how different reli