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Corporate Tax Cuts and Foreign Direct Investment

Accurate policy evaluation is central to optimal policymaking, but difficult to achieve. Most often, analysts have to work with observational data and cannot directly observe the counterfactual of a policy to assess its effect accurately. In this paper, we craft a quasi-experimental design and apply two relatively new methodsthe difference-in-differences estimation and the synthetic controls metho

Interobserver variability in the pathological assessment of radical prostatectomy specimens: Findings of the Laparoscopic Prostatectomy Robot Open (LAPPRO) study.

Abstract Objective. The aim of this study was to strengthen the validity of future findings in the Laparoscopic Prostatectomy Robot Open (LAPPRO) study by investigating the extent of interobserver variability between local pathologists and re-evaluating reference pathologists. Material and methods. LAPPRO is a Swedish prospective study comparing robot-assisted laparoscopic prostatectomy to open re

Size Distributions of Hydrometeors: Analysis with the Maximum Entropy Principle

This paper proposes that the maximum entropy principle can be used for determining the drop size distribution of hydrometeors. The maximum entropy principle can be applied to any physical systems with many degrees of freedom in order to determine a distribution of a variable when the following are known: 1) the restriction variable that leads to a homogeneous distribution without constraint and 2)

Rotational dynamics in supercooled water from nuclear spin relaxation and molecular simulations.

Structural dynamics in liquid water slow down dramatically in the supercooled regime. To shed further light on the origin of this super-Arrhenius temperature dependence, we report high-precision (17)O and (2)H NMR relaxation data for H(2)O and D(2)O, respectively, down to 37 K below the equilibrium freezing point. With the aid of molecular dynamics (MD) simulations, we provide a detailed analysis

Attenuation of Experimental Atherosclerosis by Interleukin-19.

Interleukin-19 (IL-19) is a putative Th2, anti-inflammatory interleukin. Its expression and potential role in atherogenesis are unknown. IL-19 is not detected in normal artery and is expressed to a greater degree in plaque from symptomatic versus asymptomatic patients, suggesting a compensatory counter-regulatory function. We tested whether IL-19 could reduce atherosclerosis in susceptible mice an

Climate change: changing means and changing extremes

Ongoing global warming not only involves changes in temperature and the global mean; it affects more or less every part of the climate. Regional temperature changes are often greater or smaller than corresponding changes in the global mean. In some cases the direction of change may also be different. For example, temperature changes are higher over land than over the ocean. Precipitation increases

A dose-dependent role for EBF1 in repressing non-B-cell-specific genes

In the absence of early B-cell factor 1 (EBF1), B-cell development is arrested at an uncommitted progenitor stage that exhibits increased lineage potentials. Previously, we investigated the roles of EBF1 and its DNA-binding partner Runx1 by evaluating B lymphopoiesis in single (EBF1(het) and Runx1(het)) and compound haploinsufficent (Ebf1(+/-) Runx1(+/-), ERhet) mice. Here, we demonstrate that dec

Methylation and expression analyses of Pallister-Killian syndrome reveal partial dosage compensation of tetrasomy 12p and hypomethylation of gene-poor regions on 12p.

To ascertain the epigenomic features, i.e., the methylation, non-coding RNA, and gene expression patterns, associated with gain of i(12p) in Pallister-Killian syndrome (PKS), we investigated single cell clones, harboring either disomy 12 or tetrasomy 12p, from a patient with PKS. The i(12p)-positive cells displayed a characteristic expression and methylation signature. Of all the genes on 12p, 13%

Advancing school-based interventions through economic analysis.

Commentators interested in school-based prevention programs point to the importance of economic issues for the future of prevention efforts. Many of the processes and aims of prevention science are dependent upon prevention resources. Although economic analysis is an essential tool for assessing resource use, the attention given economic analysis within school-based prevention remains cursory. Lar

Managing risk: from the United Nations to local-level realities: or vice versa

The outcomes of the Fourth Session of the Global Platform for Disaster Risk Reduction show that making cities and rural areas safe from disasters and climate change impacts and enhancing citizens' resilience is everybody's business and part of the larger sustainability challenge. Under the theme Resilient People, Resilient Planet', the session took place on 19-23 May 2013 in Geneva, Switzerland. T

Organisational frameworks for straw-based energy systems in Sweden and Denmark

This discussion highlights and defines key factors and organisational structures for the transformation of local agro-biomass based bioenery systems in Sweden and Denmark. Cross case study analysis is applied to 13 examples where straw is used for energy at various scales within a conceptual framework developed by the authors. This also delivers a cross-country comparison of systems and of the sta

Doing or Undoing Gender? An Explorative Study of Gender, Activities, and Wellbeing among People with Mental Illness Attending Day Centers in Sweden

This study explores gender, activity, and well-being among people with mental illness attending day centers in Sweden. Based on survey data of 215 attendees, this study applies the concepts of doing gender and regulatory regimes to analyze the relationship between being involved in gendered activities and wellbeing. The results show that while both male and female participants are involved in gend

Unilocular adnexal cysts with papillary projections but no other solid components: is there a diagnostic method that can reliably classify them as benign or malignant before surgery?

Aim: To develop a logistic regression model for discrimination between benign and malignant unilocular solid cysts with papillary projections but no other solid components, and to compare its diagnostic performance with that of subjective evaluation of ultrasound findings (subjective assessment), CA 125 and the risk of malignancy index (RMI). Methods: Among the 3511 adnexal masses in the Interna

Kinetics and metabolic versatility of highly tolerant phenol degrading Alcaligenes strain TW1.

A bacterium that could completely metabolize phenol in batch culture supplied with up to 1200mg phenoll(-1) at room temperature (25 degrees C) was isolated from the activated sludge of the industrial wastewater treatment plant of a Coke company (Cairo, Egypt). Morphological and physiological characterization showed strain TW1 was a motile, strictly aerobic, gram negative and short-rod occurring si

China as Chimney of the World: The Fossil Capital Hypothesis

What has caused the early 21st-century emissions explosion in China? Driving a global explosion, it appears to stand in some relation to processes of globalization, but these links have mostly remained unexplored. This article revisits some established frameworks for understanding the connection between globalization and environmental degradation and argues that they are insufficient for explainin

Scattering and inverse scattering for a left-definite Sturm-Liouville problem

This work develops a scattering and an inverse scattering theory for the Sturm-Liouville equation u '' qu = lambda wu where w may change sign but q >= 0. Thus the left-hand side of the equation gives rise to a positive quadratic form and one is led to a left-definite spectral problem. The crucial ingredient of the approach is a generalized transform built on the Jost solutions of the problem and h

A numerical and experimental investigation of the deformation zones and the corresponding cutting forces in orthogonal cutting

Abstract in UndeterminedThis study are focused on the deformation zones occurring in the work piece in a machining process and the corresponding cutting forces. The fully coupled thermo-mechanical FE-model for orthogonal cutting, developed in [1] is utilized. The work piece material is modeled with Johnson-Cook plasticity including damage formulation. Simulations for different feed depths were per