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A number of bioactive natural products have by chromatographic techniques been isolated from extracts of various fungi, and their structures have been determined by spectroscopic and chemical methods. In the screening of fungal extracts for the inhibition of the binding of various ligands to CNS receptors in rat striatal membrane preparations in vitro, bioassay-guided fractionation of extracts of
This paper is the first result of recently commenced cooperation in structural fire engineering research between the Lund Institute of Technology, and the Fire Research Department of the Technical University of Brunswick. The goal of the project is to develop improved calculation methods based on more reliable behaviour models of concrete and steel. Fox this reason tests on columns carried out at
Popular Abstract in Swedish Många biokemiska reaktioner har höga aktiveringsenergier och utan de katalyserande enzymerna skulle de flesta ämnes- omsättningsprocesser fortskrida alldeles för långsamt för att uppehålla liv. Enzymer kallas ofta för biokatalysatorer eftersom de verkar katalytiskt, dvs påskyndar kemiska reaktioner utan att själva förändras. De finns i en enorm variation eftersom vart oThis thesis addresses: (1) studies of direct and mediated electron transfer and kinetics of peroxidases on electrodes and the development of amperometric peroxidase-based biosenors, (2) electrochemical and kinetic studies of NADH oxidation at mediator modified electrodes. The direct and mediated electron transfer of horseradish and tobacco peroxidase were investigated on graphite electrodes by us
Several novel matrix molecules of cartilage and bone have recently been identified and characterized. Studies of the maturation of the femoral head give clues as to the function of the novel matrix proteins. We have studied the expression and localization of two cartilage proteins: COMP, chondroadherin (CHAD), and two bone proteins: BSP and osteoadheirn (OSAD). COMP was localized throughout cartil
The focus of this article is on product innovations introduced by firms (establishments) and the collaborations they enter into with other firms and organizations in carrying out this activity. The theoretical framework combines innovation theories with the literature on regional innovation systems and the knowledge-based economy. Empirically we have investigated characteristics of collaboration a
Background: The popularity of the open source software development in the last decade, has brought about an increased interest from the industry on how to use open source components, participate in the open source community, build business models around this type of software development, and learn more about open source development methodologies. Aim: The aim of this study is to review research ca
Historical, philological and theological comments on a selection from the Revelations of St. Birgitta of Sweden in modern Swedish translation.
Popular Abstract in Swedish Det är välkänt att utflödesobstruktion kan leda till förstoring av blåsan med åtföljande minskning av kontraktionskraften, något som kan påvisas både in vivo och in vitro. I arbete I undersöktes därför om det fanns regionala skillnader i blåsmuskelfunktion hos kaniner med experimentell utflödesobstruktion. Efter 2 veckors obstruktion utfördes cystometri och därefter undThe consequences of bladder outlet obstruction (BOO) with respect to detrusor hypertrophy, structural and functional changes, and obstruction-induced detrusor overactivity were investigated in vivo and in vitro utilizing various animal models. Possible pathophysiological pathways and therapeutic approaches were tested by drug treatment and the use of knockout models. Furthermore the role of estrog
Abstract Objectives. To compare identical versus compatible, ABO blood group matching effects on rejection and long-term survival after heart transplantation (HT). Design. Data were collected from 196 patients who underwent HT at Lund University Hospital between 1988 and 2008. Cox proportion hazard regression analysis was used to identify factors associated with reduced long-term survival. Results
Pancreatic cancer is an aggressive disease with poor prognosis, due, in part, to the lack of disease-specific biomarkers that could afford early and accurate diagnosis. With a recombinant antibody microarray platform, targeting mainly immunoregulatory proteins, we screened sera from 148 patients with pancreatic cancer, chronic pancreatitis, autoimmune pancreatitis (AIP), and healthy controls (N).
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