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Cardiac arrest – prognostic biomarkers and aspects of shock

Background: Some improvement has been seen in survival after cardiac arrest but the outcome is still poor and 50-70% of patients do not survive despite successful return of spontaneous circulation (ROSC). The cause of death is multifactorial. The majority of patients die from brain injury, but up to 35% die as a result of circulatory failure. Purpose: First, to investigate the release profiles

Evaluation of some integrals relevant to multiple scattering by randomly distributed obstacles

This paper analyzes and solves an integral and its indefinite Fourier transform of importance in multiple scattering problems of randomly distributed scatterers. The integrand contains a radiating spherical wave, and the two-dimensional domain of integration excludes a circular region of varying size. A solution of the integral in terms of radiating spherical waves is demonstrated. The method empl

The stability of AQT processing speed, ADAS-Cog and MMSE during acetylcholinesterase inhibitor treatment in Alzheimer's disease

Objectives - To explore the longitudinal stability of measures of cognition during treatment with acetylcholinesterase inhibitors (AchEI) in patients with Alzheimer's disease (AD). Materials and methods -Cognitive status was measured in a cohort of 60 patients at 6 months after initiation of treatment with AchEI (baseline) and after an additional 6 months of treatment (endpoint). A Quick Test of C

Critical comparison of performances of superficially porous particles and sub-2 mu m particles under optimized ultra-high pressure conditions

The performance of 2.7 mu m superficially porous particles at 600 bar and sub-2 mu m fully porous particles at 1000 bar were compared by the Poppe plot method. Theoretical Poppe plots were first constructed for each stationary phase to compare their kinetic performance at different analysis times. The theory was then verified by experiments under the optimized conditions identified from the Poppe

Strategier för ett ökat gående och cyklande - en litteraturstudie om olika faktorers betydelse

Denna rapport är resultatet av en litteraturstudie där olika faktorers påverkan på gåendet och cyklandet i en urban kontext har undersökts. Utifrån det studerade materialet har faktorerna delats in i grupperna individuella, externa samt resspecifika faktorer. Beslutsprocessen för genomförande av gång- och cykelresor har delats in i faserna resbeslut, färdmedelsval och vägval. De studerade publikat

Motor Vehicle speeds Recommendations for Urban Sustainability

This paper explores how vehicle speeds are related to equitable, environmental, and economic sustainability of urban areas. This relationship is manifested primarily through associations between vehicle speeds and road crash casualties, severity of pedestrian crashes, generation of harmful emissions, and relative desirability of neighboring land. Reported research findings describing these associa

Natural visual cues eliciting predator avoidance in fiddler crabs

To efficiently provide an animal with relevant information, the design of its visual system should reflect the distribution of natural signals and the animal’s tasks. In many behavioural contexts, however, we know comparatively little about the moment-to-moment information-processing challenges animals face in their daily lives. In predator avoidance, for instance, we lack an accurate description

The role of valuation practices for risk identification

This report uses a relational theory of risk within which risk is understood as a relationship between a risk object and an object at risk where the risk object threatens the value embedded in the object at risk. A case study of risk management in railway planning examined through a relational understanding of risk demonstrates how riskwork is conditioned by what is valued, how, and by whom. The r

Increased sporulation rate of epidemic clostridium difficile type 027/NAP1

Clostridium difficile PCR ribotype 027 comprised 0.2% of a collection of Swedish isolates in 1997-2001 (3 of 1,325 isolates). These isolates had lower moxifloxacin MICs than the epidemic type 027 isolates, but they had the same tcdC sequence and toxin yield. Type 027 produced 3- to 13-fold more toxin than did major Swedish types. One epidemic strain (027/NAP1a) sporulated more than did other type

Validation of urinary excretion of cyclophosphamide as a biomarker of exposure by studying its renal clearance at high and low plasma concentrations in cancer patients

OBJECTIVES: Cyclophosphamide (CP) is an alkylating agent classified as a human carcinogen. Health care workers handling this drug may be exposed during, e.g., preparation or administration. Cyclophosphamide is readily absorbed by inhalation and by dermal uptake. A biomarker, CP in urine, has frequently been used to assess the occupational exposure to CP, but has not been fully validated. The aim o

A Case Study on Software Risk Analysis in Medical Device Development

Software failures in medical devices can lead to catastrophic situations. Therefore is it crucial to handle software related risks when developing medical devices. This paper presents the experiences gained from an ongoing case study with a medical device development organisation. This part of the study focuses on the two first steps of the risk management process, i.e. risk identification and ris

Ankylosing Spondylitis Susceptibility and Severity-Contribution of TNF Gene Promoter Polymorphisms at Positions-238 and-308

Ankylosing spondylitis (AS) is a chronic inflammatory disease in which genetic factors play a central role. The efficacy of TNF blockers has reoriented research in this field in order to explain the influence of TNF in AS pathogenesis. The objective of this study was to access the influence of single nucleotide polymorphisms (SNPs) at positions -308 and -238 of the promoter region of TNF gene on A

An Optical Sensor Network for Vegetation Phenology Monitoring and Satellite Data Calibration

We present a network of sites across Fennoscandia for optical sampling of vegetation properties relevant for phenology monitoring and satellite data calibration. The network currently consists of five sites, distributed along an N-S gradient through Sweden and Finland. Two sites are located in coniferous forests, one in a deciduous forest, and two on peatland. The instrumentation consists of dual-

Prognostic role of tumour associated trypsin inhibitor in colorectal cancer patients

Colorectal cancer (CRC) is one of the most common forms of human cancer worldwide with approximately 1 million new cases detected every year. CEA is currently the only accepted CRC marker incorporated into clinical practice, where it is used for early detection of metastasis in follow-up of patients having stage II and III disease, and for monitoring response to adjuvant treatment. However there a

A prospective observational study of the effects of treatment with extended-release tolterodine on health-related quality of life of patients suffering overactive bladder syndrome in Sweden

Objective. Overactive bladder (OAB) is a chronic condition that has a profound impact on health-related quality of life (HRQoL). This study measured changes in bother of OAB symptoms and self-perceived HRQoL over 6 months in patients treated with extended-release (ER) tolterodine in a naturalistic setting. Material and methods. This was a prospective, single-cohort observational study of patients