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Personality psychology as the integrative study of traits and worldviews

Previous attempts to construct an integrative framework for personality psychology are primarily descriptions of what the field looks like today rather than analyses of its logical structure and therefore threaten to reify and perpetuate the current structure of the field. I aim here to draw attention to logically important points that may help to integrate the field and suggest potentially frui

Rättens återgång och återkomst?

Syftet med denna artikel är att mot bakgrund av Michel Foucaults föreläsningsserier vid Collège de France från senare delen av 1970-talet bidra till diskussionerna om innebörden, och riktigheten, av hans tes om att rättens betydelse för den offentligt sanktionerade maktutövningen har avtagit i modern tid. Undersökningen av denna tes inbegriper även ett klargörande av Foucaults förståelse av rätten

Estimating the effects of the container revolution on world trade

The introduction of containerization triggered complementary technological and organizational changes that revolutionized global freight transport. Despite numerous claims about the importance of containerization in stimulating international trade, econometric estimates on the effects of containerization on trade appear to be missing. Our paper fills this gap in the literature. Our key idea is to

Pancreas volume and fat fraction in children with Type 1 diabetes

AIMS: People with Type 1 diabetes have smaller pancreases than healthy individuals. Several diseases causing pancreatic atrophy are associated with pancreatic steatosis, but pancreatic fat in Type 1 diabetes has not been measured. This cross-sectional study aimed to compare pancreas size and fat fraction in children with Type 1 diabetes and controls.METHODS: The volume and fat fraction of the panc

Limited impact of fibromodulin deficiency on the development of experimental skin fibrosis

Excessive production of collagen is the hallmark of fatal diseases of fibrosis such as systemic sclerosis. Overexpression of the proteoglycan fibromodulin (FMOD) has been associated with improved wound healing and scarless repair. In this study we have investigated the consequences of FMOD deficiency on the development of experimental skin fibrosis. Using immunohistochemistry, we identified FMOD i

Additive manufacturing and its effect on sustainable design

'Sustainability' is an emerging issue that product development engineers must engage with to remain relevant, competitive and, most importantly, responsible. Yet, on examining the term 'sustainable', a plethora of definitions emerges, many of which are contradictory and confusing. This confusion and a general lack of understanding means that sustainability often gets relegated to an afterthought o

Assessing the taxonomic status of Osmoderma cristinae (Coleoptera : Scarabaeidae), endemic to Sicily, by genetic, morphological and pheromonal analyses

Resolving complexes of closely related and cryptic insect species can be challenging, especially when dealing with rare and protected taxa that are difficult to collect for genetic and morphological analyses. Until recently, populations of the genus Osmoderma (Scarabaeidae), widespread in Europe, were treated as a single species O. eremita (Scopoli, 1763) in spite of observed geographic variation

Mitotic History Reveals Distinct Stem Cell Populations and Their Contributions to Hematopoiesis

Homeostasis of short-lived blood cells is dependent on rapid proliferation of immature precursors. Using a conditional histone 2B-mCherry-labeling mouse model, we characterize hematopoietic stem cell (HSC) and progenitor proliferation dynamics in steady state and following several types of induced stress. HSC proliferation following HSC transplantation into lethally irradiated mice is fundamentall

Genome-wide RNAi Screen Identifies Cohesin Genes as Modifiers of Renewal and Differentiation in Human HSCs

To gain insights into the regulatory mechanisms of hematopoietic stem cells (HSCs), we employed a genome-wide RNAi screen in human cord-blood derived cells and identified candidate genes whose knockdown maintained the HSC phenotype during culture. A striking finding was the identification of members of the cohesin complex (STAG2, RAD21, STAG1, and SMC3) among the top 20 genes from the screen. Upon

Evidence for neural contribution to islet effects of DPP-4 inhibition in mice

It has been suggested that neural mechanisms may contribute to effects of the incretin hormones, and, therefore, also to the effects of dipeptidyl peptidase (DPP-4) inhibition. We therefore examined whether muscarinic mechanisms are involved in the stimulation of insulin secretion by DPP-4 inhibition. Fasted, anesthetized mice were given intraperitoneal saline or the muscarinic antagonist atropine

Aberrant nonfibrotic parenchyma in idiopathic pulmonary fibrosis is correlated with decreased β-catenin inhibition and increased Wnt5a/b interaction

Idiopathic pulmonary fibrosis (IPF), an insidious disease with grave prognosis, is characterized by heterogeneous fibrosis with densely fibrotic areas surrounded by nonfibrotic normal-looking tissue, believed to reflect a temporal development. The etiology is incompletely elucidated, but aberrant wound healing is believed to be involved. Embryonic signaling pathways, including Wnt signaling, are r

The Politics of Combat : The Political and Strategic Impact of Tactical-Level Subcultures, 1939-1995

This dissertation argues that lower-level military leaders, commanding between a dozen and a few hundred troops, can have a major political and strategic impact. Furthermore, it is argued that the decisions made by these lower-level military leaders are shaped by subcultures, in particular under conditions of stress and uncertainty. The concept of tactical-level subcultures is defined, drawing on

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Om den islandske forfatter Jón Kalman Stefánssons trilogi fra 2007-2011

Control-Based Load-Balancing Techniques: Analysis and Performance Evaluation via a Randomized Optimization Approach

Cloud applications are often subject to unexpected events like flashcrowds and hardware failures. Users that expect a predictable behavior may abandon an unresponsive application when these events occur. Researchers and engineers addressed this problem on two separate fronts: first, they introduced replicas - copies of the application with the same functionality - for redundancy and scalability; s

Non-genetic inheritance of induced resistance in a wild annual plant

Non-genetic inheritance, e.g. transgenerational epigenetic effects, has received increasing interest in recent years, particularly in plants. However, most studies have involved a few model species and relatively little is known about wild species in these respects. We investigated transgenerational induced resistance to infection by the devastating oomycete Phytophthora infestans in Solanum physaNon-genetic inheritance, e.g. transgenerational epigenetic effects, has received increasing interest in recent years, particularly in plants. However, most studies have involved a few model species and relatively little is known about wild species in these respects. We investigated transgenerational induced resistance to infection by the devastating oomycete Phytophthora infestans in Solanum physa