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The block of rabbit skeletal ryanodine receptors (RyR1) and dog heart RyR2 by cytosolic [Mg2+], and its reversal by agonists Ca2+, ATP and caffeine was studied in planar bilayers. Mg2+ effects were tested at submaximal activating [Ca2+] (5 microM). Approximately one third of the RyR1s had low open probability ("LA channels") in the absence of Mg2+. All other RyR1s displayed higher activity ("HA ch

Car disassembly is at the edge of extensive rationalisations due to increased legislative demands for recycling. This study focused on (1) assessing Current mechanical exposures (physical work loads) for comparison with future rationalised systems, with particular emphasis on time aspects, (2) analysing disassembly work in terms of time consumption and exposures in constituent tasks as defined by

Popular Abstract in SwedishDenna arkeologiska studie syftar till att förstå de neolitiska samhällenas framväxt, organisation och förändring kring de västskånska ådalgångarna vid Saxån-Välabäcken och Lödde å-Kävlingeån. Arkeologiska undersökningar och fornminnesinventeringen har visat att området hyser omfattande lämningar av neolitiska bebyggelsekomplex — i form av bosättningar, gravfält, megalitgThis dissertation deals with Early and Middle Neolithic societies in a valley landscape in western Scania, in the southern part of Sweden. Several archaeological excavations conducted by the National Heritage Board have revealed a great number of Neolithic remains in this region. The sites constitute a substantial continuous sequence from the earliest to the latest phase of the Funnel Beaker Cultu

OBJECTIVES:We investigated if changes in serum/plasma fibrinogen (FIB), hyaluronan (HA) and cartilage oligomeric matrix protein (COMP) levels can be used to differentiate between inflammation and cartilage involvement during arthritis. METHODS:Collagen-induced arthritis (CIA), oil-induced arthritis (OIA) and for comparison, experimental autoimmune encephalitis (EAE) induced in DA rats were investi

Abstract is not available

Bexell tecknar minnet av 78 präster. Omfattande forskningsinsatser ligger bakom den 29 sidor långa biografin över domprosten Gustaf Adolf Danell, som utreder frågan varför Danell, som uppfördes på åtta biskopsförslag, aldrig utnämndes. Ärkebiskop Brilioth sökte redan 1956 aktivt avvärja utnämning av Danell, som kritiserat biskoparnas ämbetsförvaltning och saknade kompromissförmåga. Bexell förenar

The adsorption behaviour and electronic properties of Ce@C-82 molecules on the Ag: Si(l I I)-(root3 x root3)R30degrees surface have been studied using scanning tunnelling microscopy and photoelectron spectroscopy. Submonolayer coverages and multilayer films of Ce@C-82 comprise highly ordered molecular domains which have a single, well-defined orientation with respect to the underlying substrate cr

The kinetics of furfural inhibition of the enzymes alcohol dehydrogenase (ADH; EC 1.1.1.1), aldehyde dehydrogenase (AlDH; EC 1.2.1.5) and the pyruvate dehydrogenase (PDH) complex were studied in vitro. At a concentration of less than 2 mM furfural was found to decrease the activity of both PDH and AlDH by more than 90%, whereas the ADH activity decreased by less than 20% at the same concentration.

We have investigated the effects of hilar denervation of rat liver upon the activity of hepatic lipase determined in tissue extracts. Denervated animals had an enzyme activity of 7.89 +/- 0.37 mU/mg protein, compared to 6.45 +/- 0.43 in sham-operated controls (mean +/- S.E.; P less than 0.05). We conclude that hepatic innervation may contribute to the regulation of hepatic lipase activity.

BACKGROUND: Little work has been done to investigate the suggestion that the use of selected scales from a multi-scale health-status questionnaire would compromise reliability and validity. The aim of this study was to compare the performance of three scales selected from the SF-36 generic health questionnaire when administered in isolation or within the entire SF-36 to patients with musculoskelet

We show that measurements of time-varying mobile radio channels obtained with uncalibrated correlative channel sounders are affected by four different types of systematic errors (commutation, pulse-compression, aliasing, and misinterpretation error). We analyze these errors and provide upper error bounds that are formulated in terms of channel and sounder parameters. Based on these error bounds, w

The work presented in this thesis has been focused on mesenchymal stem cells (MSCs). In the two first studies, the effects of MSCs on tumor growth and development in vitro and in vivo was investigated. In the third study the expression of the integrins alpha10beta1 and alpha11beta1 on MSCs was characterized and the involvement of these two integrins in cartilage development was investigated in vit

1. It is often assumed that lakes highly influenced by terrestrial organic matter (TOM) have low zooplankton food quality because of elemental and/or biochemical deficiencies of the major particulate organic carbon pools. We used the biochemical [polyunsaturated fatty acids, especially eicosapentaenoic acid (EPA) - 20:5 omega 3] and elemental (C : P ratio) composition of particulate matter (PM) as

"Abstract" saknas.

Both practitioners and research scientists have noted a number of problems regarding measurement activities during the past decade. The problems reported suggest that measurement activities are fragmented both within and across organizations. This article expands on a systems perspective on supply chain measurements and describes how problems can be communicated, understood and managed by developi

The adsorption of NO on Pd(1 0 0) is investigated with high resolution core level spectroscopy and low energy electron diffraction (LEED). Several ordered NO overlayers were observed, in agreement with earlier Studies. Our data clearly show that NO adsorbs in fourfold hollow sites at coverages tip to 0.25 -0.30 monolayer (ML) whereas at 0.5 ML only bridge sites are occupied. By a reinterpretation

Profound hypoglycemia causing the disappearance of spontaneous EEG activity was induced by insulin in rats. For analysis of cerebral cortical concentrations of labile phosphates, glycolytic metabolites and amino acids, the brain was frozen in situ. For microscopic analysis of the corresponding cerebral cortical areas the brain was fixed by perfusion. Hypoglycemia with an isoelectric EEG for 30 and

Microbial growth in coal slurries can be detected if surfactant is present in the samples by analysing the protein concentration after disintegration of the cells. Without surfactant present in the samples, the proteins are readily adsorbed on the coal surfaces. A suitable surfactant is sodium dodecyl sulphate at 0.5 to 1% of the sample volume