A new plesiosaur partial skeleton, comprising most of the trunk and including axial, limb, and girdle bones, was collected in the lower Sinemurian (Coimbra Formation) of Praia da Concha, near São Pedro de Moel in central west Portugal. The specimen represents a new genus and species, Plesiopharos moelensis gen. et sp. nov. Phylogenetic analysis places this taxon at the base of Plesiosauroidea. Its

Background: Women with Turner syndrome (TS) have an increased risk of aortic dissection. The current recommended cutoff to prevent aortic dissection in TS is an aortic size index (ASI) of ≥2.5 cm/m2. This study estimated which aortic size had the best predictive value for the risk of aortic dissection, and whether adjusting for body size improved risk prediction. Methods: A prospective, observatio

Background: Type III hyperlipidaemia (T3HL) is characterised by equimolar increases in plasma triglycerides (TG) and cholesterol in

Severe extratropical winter storms are a recurrent feature of the European climate and cause widespread socioeconomic losses. Due to insufficient long-term data, it remains unclear whether storminess has shown a notable response to changes in external forcing over the past millennia, which impacts our ability to project future storminess in a changing climate. Reconstructing past storm variability

This article aims at assembling the available facts concerning the exploitation of water-power in ancient and Early Mediaeval Palestine (and partly Jewish Babylonia)—those to be found in written (that is, Rabbinic) sources as well as those deriving from archaeological finds. Both groups of materials are scant, and the conclusions remain tentative. But it can be stated almost with certainty that wa

Introduction: The diagnosis of progressive supranuclear palsy (PSP) is often challenging since PSP may clinically resemble other neurodegenerative disorders. Recently, the tau PET tracer [18F]RO948, a potential new biomarker for PSP, was developed. The aim of this study was to determine the ability of three different biomarkers, including [18F]RO948 PET, to distinguish PSP patients from healthy co

Narrow dips were found in the excitation spectra of crystals of alkaline earth fluorides doped with ErF3 or/and YbF3. The positions of the dips are in good agreement with the positions of the narrow absorption lines Er3+, Yb3+ measured earlier. The absorption lines of the crystals were calculated from the excitation spectra. The observed dips in the excitation spectra are due to the absorption lin

We report a new specimen of the plesiosaur Cardiocorax mukulu that includes the most complete plesiosaur skull from sub-Saharan Africa. The well-preserved three-dimensional nature of the skull offers rare insight into the cranial anatomy of elasmosaurid plesiosaurians. The new specimen of Cardiocorax mukulu was recovered from Bentiaba, Namibe Province in Angola, approximately three meters above th

Background and Objective: Analysis of motor unit activity is important for assessing and treating diseases or injuries affecting natural movement. State-of-the-art decomposition translates high-density surface electromyography (HDsEMG) into motor unit activity. However, current decomposition methods offer far from complete separation of all motor units. Methods: This paper proposes a peel-off appr

Latest versions with source code of HIPP drawing program created within the HIPP project

The main function of a membrane is to control the exchange of matter between the surrounding regions. As such, accurate modeling of membranes is important to properly describe their properties. In many cases in both biological systems and technical applications, the membranes are composite structures where transport properties may vary between the different sub-regions of the membrane. In this wor

Numerical simulation of biomass gasification in fluidized bed reactors faces several challenges including proper modeling of the physical and chemical processes involved in the gasification and numerical stiffness of the two-phase dense particle flow problem. In this paper, the multi-phase particle-in-cell (MP-PIC) model coupled with a recently developed distribution kernel method (DKM) and a new

Pulmonary delivery of small interfering RNA (siRNA) using nanoparticle-based delivery systems is promising for local treatment of respiratory diseases. We designed dry powder inhaler formulations of siRNA-loaded lipid-polymer hybrid nanoparticles (LPNs) with aerosolization properties optimized for inhalation therapy. Interactions between LPNs and pulmonary surfactant (PS) determine the fate of inh