Lipases in the Endocannabinoid System
Lipases in the Endocannabinoid System The endocannabinoid system (ECS) is found in the central nervous system (CNS) and includes the cannabinoid receptors CB1 and CB2 [the ‘locks’], the endogenous ligands anandamide (AEA) and 2-arachidonoylglycerol (2-AG)[the ‘keys’], and the enzymes (‘locksmiths’) that make and break down these ‘keys’. Activation of the CB1 and CB2 receptors by the endocannabino
