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Anti-C1q autoantibodies are present in sera of patients with several autoimmune diseases, including systemic lupus erythematosus (SLE). Strikingly, in SLE the presence of anti-C1q is associated with the occurrence of nephritis. We have generated mouse anti-mouse C1q mAb's and used murine models to investigate whether anti-C1q autoantibodies actually contribute to renal pathology in glomerular immu

Background: Vertebral fractures are associated with back pain and disability; however, relatively little is known about the impact of radiographic vertebral fractures on quality of life in population samples. The aim of this study was to determine the impact of a recent radiographic vertebral fracture on health-related quality of life (HRQoL). Methods: Men and women aged 50 years and over were rec

Results from in vitro studies have indicated that endothelin-1 is a main candidate for endothelium-derived contracting factors. The aim of this in vivo study was to describe in quantitative terms the effects of endothelin-1 (ET-1), and of ETA receptor blockade, on vascular tone (resistance) in large-bore arterial resistance vessels (> 25 microns), small arterioles (< 25 microns) and the veins, as

The Cockcroft-Gault formula is often used to calculate the glomerular filtration rate (GFR) from plasma creatinine results. In Sweden this calculation is not usually done in the laboratory, but locally in the wards. These manual calculations could cause erroneous results. In several studies plasma cystatin C has been shown to be superior to plasma creatinine for estimation of GFR. One limitation o

In this paper a study of a career planning project launched by the Swedish National Tax Board is reported. The project, named Propeller, was initiated in 1998 as a joint endeavour among three agencies: the Swedish National Tax Board, the Regional Stockholm Tax Office and the Enforcement Authority. The intention was to create a common micro labour market in order to encourage employees to become mo

Utvärdering av mätningar på en solvärmeanläggning för en industribyggnad. Solvärmeanläggningen används för förvärmning av tappvarmvatten och för värmning av ventilationsluft till en stor maskin- och lagerhall.

Syftet med denna skrift är att exemplifiera hur man kan välja klimatdata för olika beräkningar som bör genomföras vid en fuktdimensionering. Klimatparametrarna finns sammanställda i ett PC-program som heter KLIMATDATA. Programmet är fritt tillgängligt att hämta hem. Värdena på de olika klimatparametrarna är sammanställda från tio olika meteorologiska mätstationer i Sverige för 30-årsperioden 1961-

Global error bounds are derived for full Galerkin/Runge-Kutta discretizations of nonlinear parabolic problems, including the evolution governed by the p-Laplacian with p >= 2. The analysis presented here is not based on linearization procedures, but on the fully nonlinear framework of logarithmic Lipschitz constants and an extended B-convergence theory. The global error is bounded in L-2 by Delta

Quality of life has various dimensions with multiple meanings for people. One vital issue is whether a person's subjective experienced quality of life correlates with his or her personality. Several studies show a correlation between personality and quality of life, life satisfaction or well-being. The aim of this study was to examine the relationship between personality and life quality, in parti

The investigated EO27-PO39-EO27 triblock copolymer, Pluronics P-85, is a nonionic surface-active agent which has a monomeric molecular weight of 4600, of which 500% corresponds to the PEO component. P-85 exist in complex states of aggregation in aqueous solution. Monomers, micelles and larger aggregates (clusters) coexist at lower concentrations in relative proportions which depend on temperature.

The fungicide prochloraz has got multiple mechanisms of action that may influence the demasculinizing and reproductive toxic effects of the compound. In the present study, Wistar rats were dosed perinatally with prochloraz (50 and 150 mg/kg/day) from gestational day (GD) 7 to postnatal day (PND) 16. Caesarian sections were performed on selected dams at GD 21, while others were allowed to give birt

The aim of this retrospective study was to analyze survival and prognostic factors in 111 consecutive patients undergoing curative resection of liver metastases from colorectal cancer. In addition, the time periods 1971-1984 and 1985-1995 were compared; criteria for first liver resection did not change with time, whereas the attitude toward re-resection was more aggressive during the latter period

A hollow fiber supported liquid membrane extraction method for the liquid chromatographic determination of dinitrophenolic compounds at ppt levels has been developed. Different variables affecting the extraction process, such as extraction time, shaking speed, acceptor pH, acceptor buffer concentration, salt content and humic acids have been studied. Enrichment factors up to 7000 times were obtain

A nonlinear 3D finite element model and a theoretical parameter study in relation to glued-in rods for timber structures are presented. A strain-softening crack band model was used to characterise the behaviour of the adhesive layer between the rod and the wood. The model is general in the sense that it bridges the gap between the theory of an ideal plastic bondline and the theory of linear elasti