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The origin of the Brunflo fossil meteorite and extraterrestrial chromite in mid-Ordovician limestone from the Garde quarry (Jamtland, central Sweden)

The Brunflo fossil meteorite was found in the 1950s in mid-Ordovician marine limestone in the Garde quarry in Jamtland. It originates from strata that are about 5 million years younger than similar limestone that more recently has yielded >50 fossil meteorites in the Thorsberg quarry at Kinnekulle, 600 km to the south. Based primarily on the low TiO2 content (about 1.8 wt%) of its relict chromite

Chimpanzee (Pan troglodytes) and orangutan (Pongo abelii) forethought: self-control and pre-experience in the face of future tool use.

Planning for future needs has traditionally been considered to be restricted to human cognition. Although recent studies on great ape and corvid cognition challenge this belief, the phylogenesis of human planning remains largely unknown. The complex skill for future planning has not yet been satisfactorily established in any other extant primate species than our own. In humans, planning for future

Transport and interaction blockade of cold bosonic atoms in a triple-well potential

We theoretically investigate the transport properties of cold bosonic atoms in a quasi-one-dimensional (1D) triple-well potential that consists of two large outer wells, which act as microscopic source and drain reservoirs, and a small inner well, which represents a quantum-dot-like scattering region. Bias and gate 'voltages' introduce a time-dependent tilt of the triple-well configuration, and ar

Cellular mechanisms of taxane therapy in castration resistant prostate cancer

Chemotherapy of castration resistant prostate cancer (CRPC) is based on taxane formulations worldwide. Only 30-50 % of patients respond to this therapy and the exact cellular mechanisms of taxane resistance in PC cells are not fully elucidated. There is convincing evidence that androgen receptor (AR) is affected by exposure to these compounds. The studies presented in this doctoral thesis identify

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This dissertation addresses the topic of descriptions in conversation: a relatively unexplored area of investigation apart from a small number of studies within the field of conversation analysis (Mondada 1998, 1999). However, whereas previous studies focus on the description as a social activity, enhancing the conversational facet, the present work has as a premise to put emphasis on the descript

Changes in body mass index following newly diagnosed type 2 diabetes and risk of cardiovascular mortality: A cohort study of 8486 primary-care patients

Aims. - Elevated body mass index (BMI) is associated with an increased risk of type 2 diabetes and cardiovascular disease (CVD). This study explored the association between BMI changes in the first 18 months of newly diagnosed type 2 diabetes and the risk of long-term CVD mortality. Methods. - A total of 8486 patients with newly diagnosed type 2 diabetes and no previous history of CVD or cancer we

NARX-based multi-step ahead response time prediction for database servers

Advanced telecommunication applications are often based on a multi-tier architecture, with application servers and database servers. With a rapidly increasing development of cloud computing and data centers, characterizations of the dynamics for database servers during changing workloads will be a key factor for analysis and performance improvements in these applications. We propose a multi-step a

Variable Message Signs for road tunnel emergency evacuations

This paper investigates the design of Variable Message Signs (VMS) as a way-finding aid for road tunnel emergency evacuations. The use of the Theory of Affordances is suggested to provide recommendations on the design of VMS. A preliminary evaluation of 11 selected VMS systems was performed and 6 of them were further evaluated using an affordance-based within subject stated-preference questionnair

Microvascular plasticity and neurovascular coupling in the pharmacotherapy of Parkinson's disease

Popular Abstract in Swedish Parkinsons sjukdom är en av våra mest förekommande neurologiska sjukdomar som drabbar den åldrande befolkningen. I åldersgruppen 50-60 år drabbas ca 1 procent av sjukdomen, som karakteriseras av de motoriska symptomen stelhet, långsamma rörelser och skakningar. Symptomen beror på en gradvis förlust av nervceller i en djup del av hjärnan vid namn substantia nigra (den svL-DOPA pharmacotherapy in Parkinson’s disease (PD) is associated with adverse effects occurring after a few years of treatment. Among these, dyskinesia (abnormal involuntary movements) is particularly common and potentially disabling. The causes behind dyskinesia are not completely understood, but intense research has identified a number of neuronal alterations associated with L-DOPA-induced dyski

Measurement of Tumor Extent and Effects of Breast Compression in Digital Mammography and Breast Tomosynthesis

Popular Abstract in Swedish Bröstcancer är den typ av cancer som drabbar flest kvinnor i Sverige. Årligen diagnostiseras drygt 7000 kvinnor med bröstcancer och ungefär 1400 dör av sin sjukdom. För att minska bröstcancerdödligheten rekommenderar Socialstyrelsen mammografiscreening där kvinnor över 40 år bjuds in för regelbundna kontroller. Dessa kontroller utförs med digital mammografi som innebär Breast cancer is the most common form of cancer affecting women in the western countries. Today x-ray digital mammography (DM) of the breast is commonly used for early detection of breast cancer. However, the sensitivity of mammography is limited, mainly due to the fact that a 3D volume is projected down to a 2D image. This problem can be partially solved by a tomographic technique. Breast tomosyn

Influence of selecting secondary settling tank sub-models on the calibration of WWTP models - A global sensitivity analysis using BSM2

This study investigates the sensitivity of wastewater treatment plant (WWTP) model performance to the selection of one-dimensional secondary settling tanks (1-D SST) models with first-order and second-order mathematical structures. We performed a global sensitivity analysis (GSA) on the benchmark simulation model No. 2 with the input uncertainty associated to the biokinetic parameters in the activ

Male-female differences in upregulation of vasoconstrictor responses in human cerebral arteries.

Male-female differences may significantly impact stroke prevention and treatment in men and women, however underlying mechanisms for sexual dimorphism in stroke are not understood. We previously found in males that cerebral ischemia upregulates contractile receptors in cerebral arteries, which is associated with lower blood flow. The present study investigates if cerebral arteries from men and wom

Fe-amino acid complexes immobilized on silica gel as active and highly selective catalysts in cyclohexene epoxidation

In this work, the syntheses, structure, superoxide dismutase (SOD) activity, and the catalytic use in the oxidative transformations of cyclohexene of covalently grafted Fe(III)-complexes formed with various or various combinations of C-protected amino acid (l-histidine, l-tyrosine, l-cysteine and l-cystine) ligands are presented. The structural features of the surface complexes were studied by XAN

Is the VIX futures market able to predict the VIX index? A test of the expectation hypothesis

This paper tests the expectation hypothesis by using the volatility index VIX and the futures written on that index. Because the VIX index is negatively correlated with the S&P 500 index returns the VIX futures price should contain a negative risk premium, which we do confirm in this study. When the futures price is not adjusted with the risk premium, the expectation hypothesis is rejected at

Competing 4 f-electron dynamics in Ce(Ru1-xFex)(2)Al-10 (0

We have carried out muon spin relaxation (mu SR), neutron diffraction, and inelastic neutron scattering (INS) investigations on polycrystalline samples of Ce(Ru1-xFex)(2)Al-10 (x = 0, 0.3, 0.5, 0.8, and 1) to investigate the nature of the ground state (magnetic ordered versus paramagnetic) and the origin of the spin-gap formation as evident from the bulk measurements in the end members. Our zero-f

Registered nurses' perceptions of conditions for patient education - focusing on organisational, environmental and professional cooperation aspects

Aim To describe nurses' perceptions of conditions for patient education, focusing on organisational, environmental and professional cooperation aspects, and to determine any differences between primary, municipal and hospital care. Background Although patient education is an important part of daily nursing practice, the conditions for this work are unclear and require clarification. Method A strat

International Myeloma Working Group guidelines for serum-free light chain analysis in multiple myeloma and related disorders

The serum immunoglobulin-free light chain (FLC) assay measures levels of free kappa and lambda immunoglobulin light chains. There are three major indications for the FLC assay in the evaluation and management of multiple myeloma and related plasma cell disorders (PCD). In the context of screening, the serum FLC assay in combination with serum protein electrophoresis (PEL) and immunofixation yields

Experimental evidence for a mismatch between insect emergence and waterfowl hatching under increased spring temperatures

By combining a large-scale experimental assessment on timing of insect emergence with long-term monitoring of waterfowl hatching date, we here show that insect emergence is mainly driven by temperature, whereas there is only a weak effect of increasing spring temperatures on inter-annual variability in observations of waterfowl chicks. Hence, a change in timing of the mass-emergence of insects fro

What’s in it for me? Food packaging and consumer responses in a focus group study

Purpose – This study has three broad objectives: (1) to explore consumer views on different dimensions of consumer packaging when it comes to a common staple food; (2) to discuss the role of different packaging features in consumer choice; (3) to compare consumer views on purchasing a common staple food either as an undifferentiated anonymous commodity or as a differentiated product.Design/methodo